DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment eco and RAD30

DIOPT Version :9

Sequence 1:	NP_648106.1	Gene:	eco / 38812	FlyBaseID:	FBgn0035766	Length:	1052	Species:	Drosophila melanogaster
Sequence 2:	NP_010707.3	Gene:	RAD30 / 852028	SGDID:	S000002827	Length:	632	Species:	Saccharomyces cerevisiae

Alignment Length:	342	Identity:	71/342 - (20%)
Similarity:	119/342 - (34%)	Gaps:	97/342 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 SRLRQINDDEDDADVDSLGVLPLKTHVAANRKGRSLFAAVPGKSSSSANSSP--ETNKENKKTRG 93
            ::::|.:.|...:::|     ||||...|.:    ||....|:.....:|.|  ::...||..||
Yeast   348 AKVKQSDYDRSTSNID-----PLKTADLAEK----LFKLSRGRYGLPLSSRPVVKSMMSNKNLRG 403

  Fly    94 GVMTATAEQLP--QLFTA--TMRLNSNSSSNSRNSSPRQTRVQRKRADSSMSSPTSSSE-----G 149
            ....:..:.:.  ::|.|  |.|:.......::...||..         |:|..|.|.|     |
Yeast   404 KSCNSIVDCISWLEVFCAELTSRIQDLEQEYNKIVIPRTV---------SISLKTKSYEVYRKSG 459

  Fly   150 TPSSRARNSIRRSPRTFSAQKDPDAFSSPESFQTRLSKVAAMLMKGQDSR--SMLEKSKKKHNHS 212
            ..:.:..|                 |.|.|..:..:..|..:.:||::..  .:.:.|....|..
Yeast   460 PVAYKGIN-----------------FQSHELLKVGIKFVTDLDIKGKNKSYYPLTKLSMTITNFD 507

  Fly   213 L----KTTA-----QVHTTKPKKTSPAEESQSDDEKPSSSKNSRKNTEVRETRSSQIISPKTRNR 268
            :    ||..     ||||.|      :...:.|:||.:|||...|             :||....
Yeast   508 IIDLQKTVVDMFGNQVHTFK------SSAGKEDEEKTTSSKADEK-------------TPKLECC 553

  Fly   269 RRPFTSADINCKTLKAAAHLHENMRSYDEEKTAAVKL--------ENSRSRSKSPVEVFKSNDDA 325
            :...|..|  .|.|:..|..|           .|:||        |:|::.|.....:..|....
Yeast   554 KYQVTFTD--QKALQEHADYH-----------LALKLSEGLNGAEESSKNLSFGEKRLLFSRKRP 605

  Fly   326 VKRNTGNTNNKTAKSSE 342
            ..::|.....|...||:
Yeast   606 NSQHTATPQKKQVTSSK 622

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eco	NP_648106.1	zf-C2H2_3	839..878	CDD:290589
		NAT_SF	945..>1008	CDD:173926
		Acetyltransf_13	982..1043	CDD:290591
RAD30	NP_010707.3	PolY_Pol_eta	27..505	CDD:176456	37/191 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4551
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030