DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eco and ECO1

DIOPT Version :9

Sequence 1:	NP_648106.1	Gene:	eco / 38812	FlyBaseID:	FBgn0035766	Length:	1052	Species:	Drosophila melanogaster
Sequence 2:	NP_116683.1	Gene:	ECO1 / 850584	SGDID:	S000001923	Length:	281	Species:	Saccharomyces cerevisiae

Alignment Length:	265	Identity:	66/265 - (24%)
Similarity:	114/265 - (43%)	Gaps:	73/265 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   838 NQYQIDAGQKAFGARQCQQCGLVYTVHEPEEELLHREYH------------------------NS 878
            ::.|::.|.|:....:|.:|.:.|:....|:..:|.:||                        .:
Yeast    19 SKLQVNNGSKSNKIVKCDKCEMSYSSTSIEDRAIHEKYHTLQLHGRKWSPNWGSIVYTERNHSRT 83

  Fly   879 IHVLRFKGWI------------------DEDIVSVYPEWASDGRIIRINERAPTARLDRLRDLIG 925
            :|:.|..|.|                  :|.||.|.|: .|:|.:     ||.|       :::.
Yeast    84 VHLSRSTGTITPLNSSPLKKSSPSITHQEEKIVYVRPD-KSNGEV-----RAMT-------EIMT 135

  Fly   926 VVDKELG--------YSSYIVPKIFVAFIAVRKQQIVGFCLVQPL-------SQAHRFIQVDGTD 975
            :|:.||.        ::|....| ..||:.:|..:.||..:::.|       |...|::..| :.
Yeast   136 LVNNELNAPHDENVIWNSTTEEK-GKAFVYIRNDRAVGIIIIENLYGGNGKTSSRGRWMVYD-SR 198

  Fly   976 YFSEESYP-ASCGVSRIWVSPLQRRSGIASKLLRVVQCHTVLGQEIARECIAFSTPTDDGRALAR 1039
            ...:..|| ...|:|||||....|:.|||:||:.|.:.:.|.|:.|.|..:|:|.|||.|..||.
Yeast   199 RLVQNVYPDFKIGISRIWVCRTARKLGIATKLIDVARENIVYGEVIPRYQVAWSQPTDSGGKLAS 263

  Fly  1040 QFTGL 1044
            ::.|:
Yeast   264 KYNGI 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eco	NP_648106.1	zf-C2H2_3	839..878	CDD:290589	10/62 (16%)
		NAT_SF	945..>1008	CDD:173926	22/70 (31%)
		Acetyltransf_13	982..1043	CDD:290591	27/61 (44%)
ECO1	NP_116683.1	zf-C2H2_3	18..57	CDD:404719	8/37 (22%)
ECO1	NP_116683.1	Acetyltransf_13	209..267	CDD:404721	25/57 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	52	1.000	Domainoid score	I2848
eggNOG	1	0.900	-	-		E1_KOG3014
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S5634
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002145
OrthoInspector	1	1.000	-	-		oto99486
orthoMCL	1	0.900	-	-		OOG6_102667
Panther	1	1.100	-	-	LDO	PTHR45884
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4551
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.790