Protein Alignment eco and esco1

DIOPT Version :10

• Sequence 1: NP_648106.1
• Gene: eco / 38812
• FlyBaseID: FBgn0035766
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: XP_002934171.2
• Gene: esco1 / 733526
• XenbaseID: XB-GENE-5872095
• Length: 989
• Species: Xenopus tropicalis
• Alignment Length: 1148
• Identity: 245/1148 - (21%)
• Similarity: 413/1148 - (35%)
• Gaps: 342/1148 - (29%)

  Fly    10 PSRMATPRLSERKRQLFGSPRSRLRQINDDEDDADVDSLGVLPLKTHVAANRKGRSLFAAVPGKS 74
            |||:              ||:..|::..::...|..::...:|:|..|....|.....:.:...|
 Frog    72 PSRL--------------SPQKVLQKKINERKSAKANTAKSVPVKRSVLKTTKEAPTSSRITQVS 122

  Fly    75 SSSANSSPETNK---ENKKTRGGVMTATAEQLPQLF--TATMRLNSNSSSNSRNSSPRQTRVQRK 134
            .||..:|..:.:   |||:........|::....|.  |:..||..::|..:..|   :|..:|.
 Frog   123 RSSGQASTASKRGKAENKRANMQNSKNTSKVGKNLVKNTSLARLKVSASGKNEKS---KTGTKRS 184

  Fly   135 RADSSMSSPTSSSEGTPSSRARNSIRRSPRTFSAQKDPDAFSSPESFQTRLSKVAA-----MLMK 194
            .....:....:.|:.||.:..:|...|..:|...:..|          |.:.|..|     :.::
 Frog   185 SRLLELKQGKAQSKETPKNAKKNLSIRCTKTEPLKGRP----------TSVKKTPAQNKGNIELR 239

  Fly   195 GQDSRSMLEKSKKKHNHSLKTTAQVHTTKPKKTSPAEESQSDDEKPSSSKNSRKNTEVRETRSSQ 259
            |:..|..::|.......::....:.|........|         |.||||...|..:|..|.|..
 Frog   240 GKADRKSIQKISASKESAVIGKKKAHICTITHAQP---------KESSSKKHGKQLQVTITSSQA 295

  Fly   260 IISPKTRNRRRPFTS--ADINCKTLKAAAHLHENMRSYDEEKTAAVKLENSRSRSKSPVEVFK-- 320
            ..|...:::|.|..|  :..|.||.:.     :......:....|||....|:|.|.|.|..|
 Frog   296 KKSNSRQSKRTPRLSSLSPANRKTQRG-----KTQECQGQGIKTAVKSRTLRTRVKGPNEGTKLK 355

  Fly   321 -SNDDAVKRNTGNTNNKTAKSSEVATAKRPESPGSSMKIDVEVPESDEEA--------------S 370
             ..::.:| |.| |||  .|:.|:|          |.|.:.:|.|::.:|              .
 Frog   356 AIQNEGIK-NMG-TNN--GKAIELA----------SFKSNTDVTENEVDACCLSSGVSLSKEPLE 406

  Fly   371 NHKPQKRQHPETSTPVAPSADADSGSPQSKMRKVTLSSSIPTMAFYSHSGEAVTKSRRRPSISKN 435
            ..:|.|.:...|.||..........||    :|||:                    .||.::|..
 Frog   407 KAEPTKWKTSSTDTPAKKKTPCAKASP----KKVTV--------------------ERRKTVSGT 447

  Fly   436 SLKQPTKISPTSRPLLGINKGVHHKIRKRHGFANRLPATDMDNILNSLSNERLKNLITTKREERA 500
            :..:||...|              .:.|    |.|:...|   |.|.::.|
 Frog   448 AKNKPTPSLP--------------DVPK----AKRISILD---ICNEIAGE-------------- 477

  Fly   501 KVEEVHQILRNAKDPIKMAKPLSVIEADDANNNNNLPATAWQETSADFSDLSDVEDIDPIIE--- 562
                                    ||:|......::|::            .|::..|.:||
 Frog   478 ------------------------IESDTVEVKKDVPSS------------QDMQQKDHLIEENK 506

  Fly   563 --VEP-IIPIIRHEPVQKSPTAEPADLSKRKFFKSGRRSSTCMEVRITDNIRASVSQGKIELVQT 624
              .:| .|.:...|...||        ..::||.|  |::..::.::......::...|.
 Frog   507 ESAQPEAIHLCHGEEKNKS--------HSKRFFSS--RTAVRLKCKLDRKTSPALKNSKW----- 556

  Fly   625 IRRKPRQVRVKSATIFSAEQATVD-AILKNLDDTVVDEIVEANPVVQATPIDAEETTMET--ESL 686
                 .::::..|...|......: |||.|||      :::|...:..|...|..|..:|  :.|
 Frog   557 -----NKIKLNKANNLSRMNIPRNRAILPNLD------VIKARSKLSQTGQLAASTLDKTLDKKL 610

  Fly   687 P---DIIEYAPEA--------------------------NDVEIDPFAEFRQRL-------PYQ- 714
            |   :.:.|.|::                          :|:||.....||..|       |.:
 Frog   611 PVEMNTVSYLPDSKKTKPAAIQKNKQEKTENGVLDKHINHDLEITFDEGFRLHLDSSPESSPLKK 675

  Fly   715 --TDDPNVVEQQQILLEFLISNNICTEKNFEIFIANPDDYKDEANQIVDNLYMVVNSEEAAQLAQ 777
              |..|.:..:||  ...:|::..|..|  ::|                      ||....|:|.
 Frog   676 PPTKPPQLQSEQQ--NPDVIASKACASK--QLF----------------------NSSLTDQMAP 714

  Fly   778 METVEN---TAVAIAPKQDAPAVEEVQPKLFPIFTQRLQPVVQKSLRRRPDTSMRLLTAAGGSNQ 839
            .:...|   :.|:.|....:.|              .:|..|:|......|          |:.|
 Frog   715 SDEGRNRLTSRVSSAKSTSSEA--------------NIQKEVKKLKEAEKD----------GNKQ 755

  Fly   840 YQIDAGQKAFGARQCQQCGLVYTVHEPEEELLHREYHNS-IHVLRFKGWIDEDIVSVYPEWASDG 903
            ..||||||.|||..|..||::||...||:|..|..:||. |..:::.||..|.||:.:|    ||
 Frog   756 AIIDAGQKRFGAISCNVCGMLYTASNPEDEAQHLLFHNQFISAVKYVGWKKERIVAEFP----DG 816

  Fly   904 RIIRINERAPTARLDRLRDLIGVVDKELGYSSYIVP---------KIFVAFIAVRKQQIVGFCLV 959
            |:|.:....|...|.::.::..:||.:||:..  ||         .:|::    ..:::||..:.
 Frog   817 RVIMVLPDDPKYALKKVDEIREMVDNDLGFQQ--VPLRLHSRTKTLLFIS----NDKKVVGCLIA 875

  Fly   960 QPLSQAHRFI---QVDGTD-------------YFSEESYPASCGVSRIWVSPLQRRSGIASKLLR 1008
            :.:...:|.|   ..:||.             ..|....||.||||||||..:.||..|||::|.
 Frog   876 EHIQWGYRVIDDLSPEGTSEKEKAISERVKAWCCSTSPEPAICGVSRIWVFSMMRRKKIASRMLE 940

  Fly  1009 VVQCHTVLGQEIARECIAFSTPTDDGRALARQFTGLDNFLTYD 1051
            .::.:.:.|..:.::.||||.||.||:..|.::.|...||.|:
 Frog   941 CLRNNFIYGSFLNKDEIAFSDPTPDGKLFATRYCGTSQFLVYN 983

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eco	NP_648106.1	PRK08581	189..>477	CDD:236304	65/311 (21%)
		zf-C2H2_3	839..878	CDD:464013	20/38 (53%)
		NAT_SF	945..>1008	CDD:173926	22/78 (28%)
		Acetyltransf_13	982..1050	CDD:464015	29/67 (43%)
esco1	XP_002934171.2	PTZ00121	<2..535	CDD:173412	120/622 (19%)
		zf-C2H2_3	755..794	CDD:464013	20/38 (53%)
		Acetyltransf_13	914..982	CDD:464015	29/67 (43%)