Protein Alignment eco and Esco1

DIOPT Version :10

• Sequence 1: NP_648106.1
• Gene: eco / 38812
• FlyBaseID: FBgn0035766
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: NP_001119771.2
• Gene: Esco1 / 680014
• RGDID: 1596873
• Length: 840
• Species: Rattus norvegicus
• Alignment Length: 955
• Identity: 207/955 - (21%)
• Similarity: 353/955 - (36%)
• Gaps: 227/955 - (23%)

  Fly   200 SMLEKSKKKHNHSLKTTAQVHTTKPKKTSPAEESQSDDEKPSSSKNSRKNTEVRETRSSQIISPK 264
            |:.||||:..:..:|.:...:..:     ..|.||:...|.|.||.:.|:. ||.:..|::...:
  Rat     2 SIQEKSKENSSKVIKESEGENLEQ-----EIEGSQNSLAKKSGSKEAGKSA-VRFSNKSKVNQSE 60

  Fly   265 TRNR---RRPFTSADINCKTLKAAAHLHENMRSYDEEKTAAVK---------------------- 304
            ...|   |....|||.|     |...:::||.|...:...::|
  Rat    61 IGTRMSTRSASCSADKN-----ATNSINKNMVSVKGQSQESLKKKKLCQEKLSFGTFKGSEQLNR 120

  Fly   305 -------LENSRSRS------KSPVEVFKSNDDAVKRNTGNTNNKTAKSSEVATAKRPESPGSSM 356
                   |..|.:||      :..::..|.|....:|...|:.............||     ..:
  Rat   121 RSQRLQQLTESLTRSLRSREIQGQIQTVKQNLQPARREQCNSTQSKCNKVNQKHVKR-----KVL 180

  Fly   357 KIDVEVPESDEEASNH-------KPQKRQHPETSTPVAPSADADSGSPQSKMRKVTLSSSIPTMA 414
            :|..:..|.....:|.       |.:|.||..|||..:..........|..:||.. :..:|..|
  Rat   181 EIKSDCKEDRHSVTNEVINSPKGKKRKVQHQTTSTCSSQCIQGSEKCLQKTIRKEE-TKPVPVTA 244

  Fly   415 FYSHSGEAVTKSRRRPSISKNSLKQ---PTKISPTSRPLLGINKGVHHKI----RKRHGFANRLP 472
            .......|.:...:|..:.|::..|   .||......||:. ...|.|::    :.:.|...:|.
  Rat   245 EIRKLKTATSVVSKRNELRKSAHTQVSASTKFPQIPLPLVP-EHSVDHELEQPGKSKRGSILQLC 308

  Fly   473 ATDMDNILNSLSNERLKNLITTKREER---AKVEE-------VHQ------ILRNAKDPIKMAKP 521
            ......|.:.....:.::.:.:.:||:   .|:||       :||      :..|...|.:..||
  Rat   309 EEIAGEIESDTVEVKKESCVESVKEEKPAEVKLEETDAERQTLHQKETNQDVQCNRFFPSRKTKP 373

  Fly   522 ----LSVIEADDANNNNNLPATAWQETSADFSDLSDVEDIDPIIEVEPIIPIIRHEPVQKSPTAE 582
                |:.|.:....|:|      |  |....|..:.|.......:|.|.:.::  :.....|..|
  Rat   374 VKCVLNGINSSTKKNSN------W--TKIKLSKFNSVHQHKLDSQVSPKLSLL--QTFLSPPVLE 428

  Fly   583 -PADLSKRKFFKSGRRSS-TCMEVRITDNIRASVSQG-KIELVQTIRRKPRQVRVKSATIFSAEQ 644
             |..:|:..|.:.....: ||.:    |.::...|:. ||..:        .:.:..||..:...
  Rat   429 MPHPVSQSTFLEMKPHGTVTCQQ----DKMKGIKSEDVKINNI--------AIEINKATKRAPGN 481

  Fly   645 ATVDAILKNLDDTVVDEIVEANPVVQATPIDAEETTMETESLPDIIEYAPEANDVEIDPFAEFRQ 709
            ..:|..:|...|:.:|                .:.....||.||.......|::||.:|
  Rat   482 CNLDNHIKPSSDSSLD----------------NQMKHSCESAPDQNFSICSASEVETNP------ 524

  Fly   710 RLPYQTDDPNVVEQQQILLEFLISNNICTEKNFEIFIANPDDYKDEANQIVDNLYMV--VNSEEA 772
                       :|....:...|....|..::.|      |....::.:.|:.|...:  .|.:..
  Rat   525 -----------LENTAAVSTLLSQARIDGDRKF------PGSAPNQQHSILSNEASINRKNRDTP 572

  Fly   773 AQLAQMETVENTAVAIAPK----QDAPAVEEVQPKLFPIFTQRLQPVVQKSLRRRPDTSMRLLTA 833
            ...:|::...|..:.| ||    :|:..|:|
  Rat   573 PNHSQLKCNSNLEITI-PKSLKLKDSEKVDE---------------------------------- 602

  Fly   834 AGGSNQYQIDAGQKAFGARQCQQCGLVYTVHEPEEELLHREYHNS-IHVLRFKGWIDEDIVSVYP 897
                .|..||||.|.|||..|..||::||...||:|..|..:||. |..:::.||..|.|::.||
  Rat   603 ----KQLVIDAGHKRFGAVSCNICGMLYTASNPEDETQHLLFHNQFISAVKYVGWKKERILAEYP 663

  Fly   898 EWASDGRIIRINERAPTARLDRLRDLIGVVDKELGYSS-----YIVPKIFVAFIAVRKQQIVGFC 957
                |||||.:....|...|.::.::..:||.:||:..     |...|..: ||: ..:::||..
  Rat   664 ----DGRIIMVLPEDPKYALKKVDEIREMVDNDLGFQQAPLMCYSRTKTLL-FIS-NDKKVVGCL 722

  Fly   958 LVQPLSQAHRFIQVDGTDYFSEES----------------YPASCGVSRIWVSPLQRRSGIASKL 1006
            :.:.:...:|.|:.......|||.                .||.||:|||||..:.||..|||::
  Rat   723 IAEHIQWGYRVIEEKLPVIRSEEEKVRFERQKAWCCSTLPEPAICGISRIWVFSMMRRKKIASRM 787

  Fly  1007 LRVVQCHTVLGQEIARECIAFSTPTDDGRALARQFTGLDNFLTYD 1051
            :..::.:.:.|..:::|.||||.||.||:..|.|:.|...||.|:
  Rat   788 IECLRSNFIYGSYLSKEEIAFSDPTPDGKLFATQYCGTGQFLVYN 832

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eco	NP_648106.1	PRK08581	189..>477	CDD:236304	65/328 (20%)
		zf-C2H2_3	839..878	CDD:464013	19/38 (50%)
		NAT_SF	945..>1008	CDD:173926	23/78 (29%)
		Acetyltransf_13	982..1050	CDD:464015	29/67 (43%)
Esco1	NP_001119771.2	zf-C2H2_3	604..643	CDD:464013	19/38 (50%)
		Acetyltransf_13	763..831	CDD:464015	29/67 (43%)