| Sequence 1: | NP_523957.1 | Gene: | lark / 38811 | FlyBaseID: | FBgn0011640 | Length: | 352 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_112740.1 | Gene: | HNRNPDL / 9987 | HGNCID: | 5037 | Length: | 420 | Species: | Homo sapiens |
| Alignment Length: | 376 | Identity: | 76/376 - (20%) |
|---|---|---|---|
| Similarity: | 125/376 - (33%) | Gaps: | 135/376 - (35%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 8 KLFIGNLDEKTQATELRALFEKYGTVVECDV--------VKNYGFVHMETEQQGRDAIQNLNGYT 64
Fly 65 LNEFAIKVEAAKSRRAPNTPTTKIFVGNLTDKTRAPEVRELFQKYGTVVECDIV--------RNY 121
Fly 122 GFVHLDCVGDVQDAIKELNGRVVDGQPLKV-------QVSTSRVRPKPGMGDPEQCYR------- 172
Fly 173 CGRSGHWSKECPRLYGSAGGGREPPSPLSAGGYRDRMYGRDPYPPPPPPPPFLRDRIMDGFRDYD 237
Fly 238 YYDRRFEDSRDLYERRYQTSRMRDFPPPPISRREPMPLPPTLSGSLRSCSVSRGYD-TMFSRRSP 301
Fly 302 PPPRSSNGMSRYGSPTPHGYEDFSRDAFDERMISSRGMRGPSPPGRRYAPY 352 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| lark | NP_523957.1 | RRM1_2_CoAA_like | 8..73 | CDD:409779 | 18/72 (25%) |
| RRM1_2_CoAA_like | 87..152 | CDD:409779 | 14/79 (18%) | ||
| hnRNP-R-Q | <88..>258 | CDD:273732 | 36/191 (19%) | ||
| HNRNPDL | NP_112740.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..83 | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 96..120 | ||||
| RRM1_hnRPDL | 149..224 | CDD:410152 | 18/75 (24%) | ||
| RRM2_hnRPDL | 234..308 | CDD:409998 | 16/92 (17%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 313..348 | 14/67 (21%) | |||
| Necessary for interaction with TNPO1. /evidence=ECO:0000269|PubMed:9524220 | 342..420 | 22/140 (16%) | |||
| Necessary for its nuclear import and export | 396..420 | 4/27 (15%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 398..420 | 3/21 (14%) | |||
| Blue background indicates that the domain is not in the aligned region. | |||||