DRSC/TRiP Functional Genomics Resources

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Protein Alignment lark and HRB1

DIOPT Version :10

Sequence 1:NP_523957.1 Gene:lark / 38811 FlyBaseID:FBgn0011640 Length:352 Species:Drosophila melanogaster
Sequence 2:NP_014394.2 Gene:HRB1 / 855728 SGDID:S000004949 Length:454 Species:Saccharomyces cerevisiae


Alignment Length:176 Identity:40/176 - (22%)
Similarity:68/176 - (38%) Gaps:28/176 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly     9 LFIGNLDEKTQATELRALFEKYGTVVECDVV------KNYGFVHMETEQQGRDAIQNLNGYTLNE 67
            :|:|||...:...:|...|.:.|.||..|::      :..|.|..........||:..:|....:
Yeast   163 IFVGNLTYDSTPEDLTEFFSQIGKVVRADIITSRGHHRGMGTVEFTNSDDVDRAIRQYDGAFFMD 227

  Fly    68 FAIKVEA--------AKSRRA-------PNTPTTKIFVGNLTDKTRAPEVRELFQKYGTVVECD- 116
            ..|.|..        .|.|:|       .|..|.::.|.||........::::|::.|.|...| 
Yeast   228 RKIFVRQDNPPPSNNIKERKALDRGELRHNRKTHEVIVKNLPASVNWQALKDIFKECGNVAHADV 292

  Fly   117 ------IVRNYGFVHLDCVGDVQDAIKELNGRVVDGQPLKVQVSTS 156
                  :....|.|....:.|:..||::.||..::|..|.|:...|
Yeast   293 ELDGDGVSTGSGTVSFYDIKDLHRAIEKYNGYSIEGNVLDVKSKES 338

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
larkNP_523957.1 RRM1_2_CoAA_like 8..73 CDD:409779 16/69 (23%)
RRM1_2_CoAA_like 87..152 CDD:409779 16/71 (23%)
hnRNP-R-Q <88..>258 CDD:273732 18/76 (24%)
HRB1NP_014394.2 PRK12678 <29..>85 CDD:237171
RRM1_HRB1_GBP2 160..236 CDD:410184 17/72 (24%)
RRM2_HRB1_GBP2 262..334 CDD:410185 16/71 (23%)
RRM3_HRB1_GBP2 374..452 CDD:410186
Blue background indicates that the domain is not in the aligned region.

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