DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lark and Srsf1

DIOPT Version :9

Sequence 1:	NP_523957.1	Gene:	lark / 38811	FlyBaseID:	FBgn0011640	Length:	352	Species:	Drosophila melanogaster
Sequence 2:	NP_001103022.1	Gene:	Srsf1 / 689890	RGDID:	1587490	Length:	248	Species:	Rattus norvegicus

Alignment Length:	270	Identity:	67/270 - (24%)
Similarity:	95/270 - (35%)	Gaps:	83/270 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    87 KIFVGNLTDKTRAPEVRELFQKYGTVVECDIVRNYG-----FVHLDCVGDVQDAIKELNGRVVDG 146
            :|:||||....|..::.::|.|||.:.:.|:....|     ||..:...|.:||:...:|...||
  Rat    17 RIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVEFEDPRDAEDAVYGRDGYDYDG 81

  Fly   147 QPLKVQVSTSRVRPKPGMGDPEQCYRCGRSGHWSKECPRLYGSAGGGREPPSPLSAGGYRDRMYG 211
            ..|:|:.      |:.|.|       .||.|          |..|||..|
  Rat    82 YRLRVEF------PRSGRG-------TGRGG----------GGGGGGGAP--------------- 108

  Fly   212 RDPYPPP-------------PPPPPF--LRDRI--------MDGFR------------DYDYYDR 241
            |..|.||             ||...:  |:|.:        .|.:|            |..|..|
  Rat   109 RGRYGPPSRRSENRVVVSGLPPSGSWQDLKDHMREAGDVCYADVYRDGTGVVEFVRKEDMTYAVR 173

  Fly   242 RFEDSRDLYERRYQTSRMR---DFPPPPISRREPMPLPPTLSGSLRSCSVSRGYDTMFSRRSPP- 302
            :.:::: ......:|:.:|   |.|..|...|.............||.|.||.|....||.||.
  Rat   174 KLDNTK-FRSHEGETAYIRVKVDGPRSPSYGRSRSRSRSRSRSRSRSNSRSRSYSPRRSRGSPRY 237

  Fly   303 PPRSSNGMSR 312
            .||.|...||
  Rat   238 SPRHSRSRSR 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lark	NP_523957.1	RRM1_2_CoAA_like	8..73	CDD:409779
		RRM1_2_CoAA_like	87..152	CDD:409779	21/69 (30%)
		hnRNP-R-Q	<88..>258	CDD:273732	47/209 (22%)
Srsf1	NP_001103022.1	RRM1_SRSF1	12..90	CDD:410010	22/78 (28%)
Srsf1	NP_001103022.1	RRM2_SRSF1	113..196	CDD:410160	13/83 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910