Protein Alignment lark and TRA2B

DIOPT Version :10

• Sequence 1: NP_523957.1
• Gene: lark / 38811
• FlyBaseID: FBgn0011640
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: NP_004584.1
• Gene: TRA2B / 6434
• HGNCID: 10781
• Length: 288
• Species: Homo sapiens
• Alignment Length: 261
• Identity: 63/261 - (24%)
• Similarity: 89/261 - (34%)
• Gaps: 101/261 - (38%)

  Fly    79 RAPNTPTTKIFVGNLTDKTRAPEVRELFQKYGTVVECDIV--------RNYGFVHLDCVGDVQDA 135
            ||...|...:.|..|:..|...::||:|.|||.:.:..||        |.:.||:.:.|.|.::|
Human   111 RANPDPNCCLGVFGLSLYTTERDLREVFSKYGPIADVSIVYDQQSRRSRGFAFVYFENVDDAKEA 175

  Fly   136 IKELNGRVVDGQPLKVQVS-TSRVR-PKPG--MGDPEQCYRCGRSGHWSKECPRLYGSAGGGREP 196
            .:..||..:||:.::|..| |.|.. |.||  ||.|                  .|||:
Human   176 KERANGMELDGRRIRVDFSITKRPHTPTPGIYMGRP------------------TYGSS------ 216

  Fly   197 PSPLSAGGYRDRMYGRDPYPPPPPPPPFLRDRIMDGFRDYDYYDRRFE---DSRDLYERRYQTSR 258
                                                 |..|||||.::   |.||.|.|.|:..
Human   217 -------------------------------------RRRDYYDRGYDRGYDDRDYYSRSYRGG- 243

  Fly   259 MRDFPPPPISRREPMPLPPTLSGSLRSCSVSRGYDTMFSRRSPPPPRSSNG---MSRYGSPTPHG 320
                                 .|.......::..|.::.||||.|..|..|   .||..|.:|..
Human   244 ---------------------GGGGGGWRAAQDRDQIYRRRSPSPYYSRGGYRSRSRSRSYSPRR 287

  Fly   321 Y 321
            |
Human   288 Y 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lark	NP_523957.1	RRM1_2_CoAA_like	8..73	CDD:409779
		RRM1_2_CoAA_like	87..152	CDD:409779	21/72 (29%)
		hnRNP-R-Q	<88..>258	CDD:273732	46/184 (25%)
TRA2B	NP_004584.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..114		2/2 (100%)
		RRM_TRA2	117..196	CDD:409798	23/78 (29%)
		Linker	193..230		18/97 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	196..225		16/89 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	242..288		13/67 (19%)