DRSC/TRiP Functional Genomics Resources

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Protein Alignment lark and SRSF7

DIOPT Version :9

Sequence 1:NP_523957.1 Gene:lark / 38811 FlyBaseID:FBgn0011640 Length:352 Species:Drosophila melanogaster
Sequence 2:NP_001026854.1 Gene:SRSF7 / 6432 HGNCID:10789 Length:238 Species:Homo sapiens


Alignment Length:270 Identity:79/270 - (29%)
Similarity:107/270 - (39%) Gaps:65/270 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    86 TKIFVGNLTDKTRAPEVRELFQKYGTVVECDIVRN---YGFVHLDCVGDVQDAIKELNGRVVDGQ 147
            ||::||||.......|:...|..||.:....|.||   :.||..:...|.:||::.|:|:|:.|.
Human    11 TKVYVGNLGTGAGKGELERAFSYYGPLRTVWIARNPPGFAFVEFEDPRDAEDAVRGLDGKVICGS 75

  Fly   148 PLKVQVSTSRVR-------PKPGMGDP-EQCYRCGRSGHWSKECPRLYGSAGGGREPPSPLSAGG 204
            .::|::||...|       |.....|| ::||.||..||::.:|.| |......|......|.. 
Human    76 RVRVELSTGMPRRSRFDRPPARRPFDPNDRCYECGEKGHYAYDCHR-YSRRRRSRSRSRSHSRS- 138

  Fly   205 YRDRMYGRDPYPPPPPPPPFLRDRIMDGFRDYDYYDRRFEDSRDLYERRYQTSRMRD-------- 261
             |.|.|.|.            |.| ..|.|......||   ||.:..||.:::.:|.        
Human   139 -RGRRYSRS------------RSR-SRGRRSRSASPRR---SRSISLRRSRSASLRRSRSGSIKG 186

  Fly   262 ---FPPPPISRREPMPLPPTLSGSLRSCSVSRGYDTMFSRRSPPPPRSSNGMSRYGSPTPHGYED 323
               |..|..||.             ||.|:||...:....|||.|.||   .|..|||       
Human   187 SRYFQSPSRSRS-------------RSRSISRPRSSRSKSRSPSPKRS---RSPSGSP------- 228

  Fly   324 FSRDAFDERM 333
             .|.|..|||
Human   229 -RRSASPERM 237

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
larkNP_523957.1 RRM1_2_CoAA_like 8..73 CDD:409779
RRM1_2_CoAA_like 87..152 CDD:409779 21/67 (31%)
hnRNP-R-Q <88..>258 CDD:273732 52/180 (29%)
SRSF7NP_001026854.1 RRM_SRSF7 12..88 CDD:410050 24/75 (32%)
Sufficient for interaction with NXF1 81..98 4/16 (25%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 123..238 41/157 (26%)
6 X 8 AA repeats of R-R-S-R-S-X-S-X 153..226 24/91 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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