Protein Alignment lark and SRSF5

DIOPT Version :10

• Sequence 1: NP_523957.1
• Gene: lark / 38811
• FlyBaseID: FBgn0011640
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: NP_008856.2
• Gene: SRSF5 / 6430
• HGNCID: 10787
• Length: 272
• Species: Homo sapiens
• Alignment Length: 242
• Identity: 56/242 - (23%)
• Similarity: 101/242 - (41%)
• Gaps: 43/242 - (17%)

  Fly     8 KLFIGNLDEKTQATELRALFEKYGTVVECDVVKNYGFVHMETEQQGRDAIQNLNGYTLNEFAIKV 72
            ::|||.|:...:..::...|:.||.:.:.|:.:.:|||..|..:...||:..|:|..|....:.:
Human     5 RVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGKELCSERVTI 69

  Fly    73 EAAKSR----------------RAP-----NTP----TTKIFVGNLTDKTRAPEVRELFQKYGTV 112
            |.|::|                |.|     |.|    ..::.|.||:.:....::::..::.|.|
Human    70 EHARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVSWQDLKDFMRQAGEV 134

  Fly   113 VECDIVR---NYGFVHLDCVGDVQDAIKELNGRVVDGQPLKV-----QVSTSRVRPKPGMGDPEQ 169
            ...|..|   |.|.|.....||:::||::|:|:.::|:.:|:     :.|.||.|.:...
Human   135 TFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIEGSKRHSRSRSRSRSRT----- 194

  Fly   170 CYRCGRSGHWSKECPRLYGSAGGGREPPSPLSAGGYRDRMYGRDPYP 216
                 ||...|:...|........|......|....:.|...|.|.|
Human   195 -----RSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVP 236

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lark	NP_523957.1	RRM1_2_CoAA_like	8..73	CDD:409779	17/64 (27%)
		RRM1_2_CoAA_like	87..152	CDD:409779	18/72 (25%)
		hnRNP-R-Q	<88..>258	CDD:273732	32/137 (23%)
SRSF5	NP_008856.2	RRM1_SRSF5	5..74	CDD:410008	19/68 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	73..105		5/31 (16%)
		RRM2_SRSF5	99..179	CDD:410158	20/79 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	174..272		15/73 (21%)