Protein Alignment lark and SRSF4

DIOPT Version :9

• Sequence 1: NP_523957.1
• Gene: lark / 38811
• FlyBaseID: FBgn0011640
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: NP_005617.2
• Gene: SRSF4 / 6429
• HGNCID: 10786
• Length: 494
• Species: Homo sapiens
• Alignment Length: 367
• Identity: 82/367 - (22%)
• Similarity: 133/367 - (36%)
• Gaps: 75/367 - (20%)

  Fly     8 KLFIGNLDEKTQATELRALFEKYGTVVECDVVKNYGFVHMETEQQGRDAIQNLNGYTLNEFAIKV 72
            :::||.|..:.:..::...|:.||.::|.|:...||||..:..:...||:..|||..|....:.|
Human     3 RVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGKDLCGERVIV 67

  Fly    73 EAAKSRR----------------------APNTPTT-KIFVGNLTDKTRAPEVRELFQKYGTVVE 114
            |.|:..|                      .|.|.|. ::.|.||:.:....::::..::.|.|..
Human    68 EHARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDLKDYMRQAGEVTY 132

  Fly   115 CDI---VRNYGFVHLDCVGDVQDAIKELNGRVVDGQPLKVQVSTSRVRPKPGMGDPEQCYRCGRS 176
            .|.   .:|.|.:......|::.|:::|:|..|:|:.:::      |..|||.       |..||
Human   133 ADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRL------VEDKPGS-------RRRRS 184

  Fly   177 GHWSKECPRLYGSAGGGREPPSPLSAGGYRDRMYGRDPYPPPPPPPPFLRDRIMDGFRDYDYYDR 241
            ...|:...|   |....|......|..|.....:.:.            |.|...|.|
Human   185 YSRSRSHSR---SRSRSRHSRKSRSRSGSSKSSHSKS------------RSRSRSGSR------- 227

  Fly   242 RFEDSRDLYERRYQTSRMRDFPPPPISRREPMPLPPTLSGSLRSCSVSRGYDTMFSRRSPPPPRS 306
                ||.....|.| ||.|       |::|....|.......||.|..:.......:.......:
Human   228 ----SRSKSRSRSQ-SRSR-------SKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNN 280

  Fly   307 SN-GMSRYGSPTPHGYEDFSRDAFDERMISSRGMRGPSPPGR 347
            .| |..:..||:.|..:..||....||.:... .||....||
Human   281 DNVGKPKSRSPSRHKSKSKSRSRSQERRVEEE-KRGSVSRGR 321

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lark	NP_523957.1	RRM1_2_CoAA_like	8..73	CDD:409779	18/64 (28%)
		RRM1_2_CoAA_like	87..152	CDD:409779	14/67 (21%)
		hnRNP-R-Q	<88..>258	CDD:273732	35/172 (20%)
SRSF4	NP_005617.2	RRM1_SRSF4_like	3..72	CDD:240783	21/68 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	72..95		1/22 (5%)
		RRM2_SRSF4_like	104..175	CDD:241044	15/76 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	169..494		43/201 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910