DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lark and elavl3

DIOPT Version :9

Sequence 1:	NP_523957.1	Gene:	lark / 38811	FlyBaseID:	FBgn0011640	Length:	352	Species:	Drosophila melanogaster
Sequence 2:	XP_012808614.1	Gene:	elavl3 / 594912	XenbaseID:	XB-GENE-490864	Length:	363	Species:	Xenopus tropicalis

Alignment Length:	167	Identity:	44/167 - (26%)
Similarity:	74/167 - (44%)	Gaps:	20/167 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LFIGNLDEKTQATELRALFEKYGTVVECDVVKN--------YGFVHMETEQQGRDAIQNLNGYTL 65
            |.:..|.:.....|.::||...|.:..|.:|::        ||||:.........||..|||..|
Frog    37 LIVNYLPQNMTQEEFKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYVDPNDADKAINTLNGLKL 101

  Fly    66 NEFAIKVEAAKSRRAPNTPTTKIFVGNLTDKTRAPEVRELFQKYGTVVECDIV---------RNY 121
            ....|||..|:...| :.....::|.:|.......|:.:||.:||.::...|:         |..
Frog   102 QTKTIKVSYARPSSA-SIRDANLYVSSLPKTMNQKEMEQLFSQYGRIITSRILVDQVTGSVSRGV 165

  Fly   122 GFVHLDCVGDVQDAIKELNGRVVDG--QPLKVQVSTS 156
            ||:..|...:.::|||.|||:...|  :|:.|:.:.:
Frog   166 GFIRFDKRIEAEEAIKGLNGQKPLGASEPITVKFANN 202

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lark	NP_523957.1	RRM1_2_CoAA_like	8..73	CDD:409779	20/71 (28%)
		RRM1_2_CoAA_like	87..152	CDD:409779	20/75 (27%)
		hnRNP-R-Q	<88..>258	CDD:273732	21/80 (26%)
elavl3	XP_012808614.1	ELAV_HUD_SF	32..362	CDD:273741	44/167 (26%)
		RRM1_Hu	34..111	CDD:241094	21/73 (29%)
		RRM_SF	116..206	CDD:302621	22/88 (25%)
		RRM3_HuC	279..363	CDD:241099
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910