DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lark and SF2

DIOPT Version :9

Sequence 1:	NP_523957.1	Gene:	lark / 38811	FlyBaseID:	FBgn0011640	Length:	352	Species:	Drosophila melanogaster
Sequence 2:	NP_001247139.1	Gene:	SF2 / 53443	FlyBaseID:	FBgn0283477	Length:	255	Species:	Drosophila melanogaster

Alignment Length:	290	Identity:	73/290 - (25%)
Similarity:	101/290 - (34%)	Gaps:	82/290 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    87 KIFVGNLTDKTRAPEVRELFQKYGTVVECDIVRNYG----FVHLDCVGDVQDAIKELNGRVVDGQ 147
            :|:||||....|..::::||.|:|.|...|:....|    ||..:...|..||:|..:|...||.
  Fly     8 RIYVGNLPPDIRTKDIQDLFHKFGKVTFVDLKNRRGPPFAFVEFEDARDADDAVKARDGYDYDGY 72

  Fly   148 PLKVQVSTSRVRPKPGMGDPEQCYRCGRSGHWSKECPRLYGSAGGGREPPSPLS----------- 201
            .|:|:.        |..|.|.. ||.|.....|::    .|...|||.||:..|
  Fly    73 RLRVEF--------PRGGGPGS-YRGGNRNDRSRD----GGGRMGGRGPPAKRSQYRVMVTGLPA 124

  Fly   202 AGGYRD-----RMYG----RDPYPPPPPPPPFLRDRIMDGFRDYDYYDRRFEDSR-DLYERRYQT 256
            :|.::|     |..|    .|.|........|||      ..|..|..::.:||| ..:|.....
  Fly   125 SGSWQDLKDHMREAGDVCFADTYKDGSGVVEFLR------HEDMKYAIKKLDDSRFRSHEGEVAY 183

  Fly   257 SRMRDFPPPPISRREPMPLPPTLSGSLRSCSVSRGYDTMFSRRSPPPPRSSNGMSRYGSPTPHGY 321
            .|:|:                               |:..:.|......|..|....|......|
  Fly   184 IRVRE-------------------------------DSGDNDRGGGGGGSGGGGGGSGGGGSRDY 217

  Fly   322 EDFSRDAFDERMISSRGMRGPSP---PGRR 348
            .|.||    .|..|||..|..:|   |.||
  Fly   218 RDRSR----SRSFSSRPRRRGTPTYSPVRR 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lark	NP_523957.1	RRM1_2_CoAA_like	8..73	CDD:409779
		RRM1_2_CoAA_like	87..152	CDD:409779	23/68 (34%)
		hnRNP-R-Q	<88..>258	CDD:273732	53/194 (27%)
SF2	NP_001247139.1	RRM_SF	3..80	CDD:418427	24/79 (30%)
SF2	NP_001247139.1	RRM2_SRSF1_like	115..188	CDD:410013	16/78 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23147
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010