DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lark and Srsf7

DIOPT Version :9

Sequence 1:	NP_523957.1	Gene:	lark / 38811	FlyBaseID:	FBgn0011640	Length:	352	Species:	Drosophila melanogaster
Sequence 2:	NP_001034124.2	Gene:	Srsf7 / 362687	RGDID:	1307425	Length:	238	Species:	Rattus norvegicus

Alignment Length:	273	Identity:	77/273 - (28%)
Similarity:	106/273 - (38%)	Gaps:	71/273 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    86 TKIFVGNLTDKTRAPEVRELFQKYGTVVECDIVRN---YGFVHLDCVGDVQDAIKELNGRVVDGQ 147
            ||::||||.......|:...|..||.:....|.||   :.||..:...|.:||::.|:|:|:.|.
  Rat    11 TKVYVGNLGTGAGKGELERAFSYYGPLRTVWIARNPPGFAFVEFEDPRDAEDAVRGLDGKVICGS 75

  Fly   148 PLKVQVSTSRVR-------PKPGMGDP-EQCYRCGRSGHWSKECPRLYGSAGGGREPPSPLSAGG 204
            .::|::||...|       |.....|| ::||.||..||::.:|.| |......|......|..
  Rat    76 RVRVELSTGMPRRSRFDRPPARRPFDPNDRCYECGEKGHYAYDCHR-YSRRRRSRSRSRSHSRS- 138

  Fly   205 YRDRMYGRDPYPPPPPPPPFLRDRIMDGFRDYDYYDRRFEDSRDLYERRYQTSRMRDFPPPPISR 269
             |.|.|.|.            |.|            .|...||....||.::..:|        |
  Rat   139 -RGRRYSRS------------RSR------------SRGRRSRSASPRRSRSVSLR--------R 170

  Fly   270 REPMPLPPTLSGSL--------------RSCSVSRGYDTMFSRRSPPPPRSSNGMSRYGSPTPHG 320
            .....|..:.|||:              ||.|:||...:....|||.|.|     ||..|.:||
  Rat   171 SRSASLRRSRSGSIIGSRYFQSRSRSRSRSRSISRPRSSRSKSRSPSPKR-----SRSPSGSPH- 229

  Fly   321 YEDFSRDAFDERM 333
                 |.|..|||
  Rat   230 -----RSASPERM 237

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lark	NP_523957.1	RRM1_2_CoAA_like	8..73	CDD:409779
		RRM1_2_CoAA_like	87..152	CDD:409779	21/67 (31%)
		hnRNP-R-Q	<88..>258	CDD:273732	49/180 (27%)
Srsf7	NP_001034124.2	RRM_SRSF7	12..88	CDD:410050	24/75 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910