Protein Alignment lark and TRA2A

DIOPT Version :10

• Sequence 1: NP_523957.1
• Gene: lark / 38811
• FlyBaseID: FBgn0011640
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: NP_037425.1
• Gene: TRA2A / 29896
• HGNCID: 16645
• Length: 282
• Species: Homo sapiens
• Alignment Length: 200
• Identity: 62/200 - (31%)
• Similarity: 87/200 - (43%)
• Gaps: 46/200 - (23%)

  Fly    79 RAPNTPTTKIFVGNLTDKTRAPEVRELFQKYGTVVECDIV--------RNYGFVHLDCVGDVQDA 135
            ||...|.|.:.|..|:..|...::||:|.:||.:...::|        |.:.||:.:.:.|.::|
Human   112 RANPDPNTCLGVFGLSLYTTERDLREVFSRYGPLSGVNVVYDQRTGRSRGFAFVYFERIDDSKEA 176

  Fly   136 IKELNGRVVDGQPLKVQVS-TSRVR-PKPG--MGDPEQCYRCGRSGHWSKECPRLYGSAGGGREP 196
            ::..||..:||:.::|..| |.|.. |.||  ||.|......|..|...       |..||||..
Human   177 MERANGMELDGRRIRVDYSITKRAHTPTPGIYMGRPTHSGGGGGGGGGG-------GGGGGGRRR 234

  Fly   197 PSPLSAGGYRDRMYGRDPYPPPPPPPPFLRDRIMDGFRDYDY-YDRRFEDSRDLYERRYQT-SRM 259
            .|      |.||.|                ||..|.:.|||| |.||   |...|..||:: ||.
Human   235 DS------YYDRGY----------------DRGYDRYEDYDYRYRRR---SPSPYYSRYRSRSRS 274

  Fly   260 RDFPP 264
            |.:.|
Human   275 RSYSP 279

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lark	NP_523957.1	RRM1_2_CoAA_like	8..73	CDD:409779
		RRM1_2_CoAA_like	87..152	CDD:409779	18/72 (25%)
		hnRNP-R-Q	<88..>258	CDD:273732	54/183 (30%)
TRA2A	NP_037425.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..118		2/5 (40%)
		RRM_TRA2	118..197	CDD:409798	21/78 (27%)
		Linker	198..225		9/26 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	201..245		19/72 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	260..282		7/19 (37%)