DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lark and Pabpc6

DIOPT Version :9

Sequence 1:	NP_523957.1	Gene:	lark / 38811	FlyBaseID:	FBgn0011640	Length:	352	Species:	Drosophila melanogaster
Sequence 2:	NP_001099678.1	Gene:	Pabpc6 / 292295	RGDID:	1311201	Length:	643	Species:	Rattus norvegicus

Alignment Length:	406	Identity:	92/406 - (22%)
Similarity:	161/406 - (39%)	Gaps:	87/406 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 AGTFKLFIGNLDEKTQATELRALFEKYGTVVECDVV------KNYGFVHMETEQQGRDAIQNLNG 62
            :|...:|:.|||....:..|...|..:|.::.|.||      |.|||||.||:::...||:.:||
  Rat    96 SGVGNIFVKNLDRSIDSKTLYDTFSAFGNILSCKVVCDENGSKGYGFVHFETQEEAERAIEKMNG 160

  Fly    63 YTLNEFAIKVEAAKSRR-------APNTPTTKIFVGNLTDKTRAPEVRELFQKYGTVVECDIV-- 118
            ..||:..:.|...||||       |.....|.:::.||.:......:::||.::|..:...::
  Rat   161 MFLNDRKVFVGRFKSRRDRQAELGARAKEFTNVYIKNLGEDMDDERLQDLFSRFGPALSVKVMTD 225

  Fly   119 -----RNYGFVHLDCVGDVQDAIKELNGRVVDGQPLKVQVSTSRV----------------RPKP 162
                 :.:|||..:...|.:.|:.|:||:.::|:.:.|..:..:|                :||.
  Rat   226 ESGKSKGFGFVSFERHEDARKAVDEMNGKDLNGKQIYVGRAQKKVERQTELKHKFGQMKQDKPKI 290

  Fly   163 GMGDPEQCYRCGRSGHWSK------ECPRLYGSAGGGREPPSP--------LSAGGYRDRMYGRD 213
            .....::..||.....:.|      :..||       |:..||        ::..|.|.:.:|..
  Rat   291 EQVPQDRSVRCQGVNLYVKNLDDGIDDERL-------RKEFSPFGTITSAKVTMEGGRSKGFGFV 348

  Fly   214 PYPPPPPPPPFLRD---RIMDGFRDYDYYDRRFED-----SRDLYERRYQTSRMRDFPPPPISRR 270
            .:..|......:.:   ||:.....|....:|.|:     |....:|...||.:   |.|.|:
  Rat   349 CFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQAHLSNQYMQRMASTSAV---PNPGIN-- 408

  Fly   271 EPMPLPPT--LSGSLRSCSV---SRGYDTMFSRRSPPPPRSSNGMSRYGS---PTPHGYEDFSRD 327
               |..|.  |||...:.:.   :||  |.::    |...:..|.|..||   ...|.:::.|..
  Rat   409 ---PFQPAQGLSGYFMTATAPTQNRG--TYYA----PNQTTQQGPSARGSAQGTRAHPFQNMSSA 464

  Fly   328 AFDERMISSRGMRGPS 343
            ......:.|....||:
  Rat   465 IHPSNTMPSFSTSGPT 480

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lark	NP_523957.1	RRM1_2_CoAA_like	8..73	CDD:409779	24/70 (34%)
		RRM1_2_CoAA_like	87..152	CDD:409779	14/71 (20%)
		hnRNP-R-Q	<88..>258	CDD:273732	38/214 (18%)
Pabpc6	NP_001099678.1	PABP-1234	11..622	CDD:130689	92/406 (23%)
		RRM1_I_PABPs	12..91	CDD:240824
		RRM2_I_PABPs	97..172	CDD:240825	26/74 (35%)
		RRM3_I_PABPs	190..269	CDD:240826	16/78 (21%)
		RRM4_I_PABPs	303..380	CDD:240827	13/83 (16%)
		PABP	555..621	CDD:279051
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910