DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lark and Srsf9

DIOPT Version :9

Sequence 1:	NP_523957.1	Gene:	lark / 38811	FlyBaseID:	FBgn0011640	Length:	352	Species:	Drosophila melanogaster
Sequence 2:	XP_038945194.1	Gene:	Srsf9 / 288701	RGDID:	1309495	Length:	247	Species:	Rattus norvegicus

Alignment Length:	269	Identity:	69/269 - (25%)
Similarity:	97/269 - (36%)	Gaps:	79/269 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    87 KIFVGNLTDKTRAPEVRELFQKYGTVVECDIVRNYGFVHLDCV--GDVQDAIKELNGRVVDGQ-- 147
            :|:||||....|..::.:||.|||.:.|.::...:|.|....|  .|.:..::.|.||....|
  Rat    15 RIYVGNLPTDVREKDLEDLFYKYGRIREIELKNRHGLVPFAFVRFEDPRHGLRALTGRNSKSQRS 79

  Fly   148 -----PLKVQVSTSRVRPKPGMGDPEQCYRCGRSGHWSKEC------PRLYGSAGG----GREPP 197
                 ||.|.             |.|... .||:|:...:|      ||.||..||    .|..|
  Rat    80 AFLWLPLLVT-------------DAEDAI-YGRNGYDYGQCRLRVEFPRAYGGRGGWPRASRNGP 130

  Fly   198 SPLSAGGYRDRMYGRDPYPPPPPPPPFLRDRI------------MDGF--------RDYDYYDRR 242
             |.....:|..:.|.    ||......|:|.:            .||.        .|.:|..|:
  Rat   131 -PTRRSDFRVLVSGL----PPSGSWQDLKDHMREAGDVCYADVQKDGMGMVEYLRKEDMEYALRK 190

  Fly   243 FEDSRDLYERRYQTSRMRDFPPPPISRREPMPLPPTLSGSLRSCSVSRGYDTMFSRRSPPPPRSS 307
            .:|:: ......:||.:|.:|.           ..|..|..||.|.|||.|:         |..|
  Rat   191 LDDTK-FRSHEGETSYIRVYPE-----------RGTSYGCSRSRSGSRGRDS---------PYQS 234

  Fly   308 NGMSRYGSP 316
            .|...|.||
  Rat   235 RGSPHYFSP 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lark	NP_523957.1	RRM1_2_CoAA_like	8..73	CDD:409779
		RRM1_2_CoAA_like	87..152	CDD:409779	22/73 (30%)
		hnRNP-R-Q	<88..>258	CDD:273732	51/208 (25%)
Srsf9	XP_038945194.1	RRM1_SRSF9	15..112	CDD:241042	29/110 (26%)
Srsf9	XP_038945194.1	RRM2_SRSF9	129..212	CDD:410161	18/99 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910