DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment lark and rsp-2

DIOPT Version :9

Sequence 1:	NP_523957.1	Gene:	lark / 38811	FlyBaseID:	FBgn0011640	Length:	352	Species:	Drosophila melanogaster
Sequence 2:	NP_496441.1	Gene:	rsp-2 / 174747	WormBaseID:	WBGene00004699	Length:	281	Species:	Caenorhabditis elegans

Alignment Length:	324	Identity:	73/324 - (22%)
Similarity:	104/324 - (32%)	Gaps:	120/324 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    87 KIFVGNLTDKTRAPEVRELFQKYGTVVECDIVRNYGFVHLDCVGDVQDAIKELNGRVVDGQPLKV 151
            ::::|.|.::....:|...|:.||.:.:..:...:|||......|..||:.:|||:.:.|:.:.:
Worm     3 RVYIGRLPNRASDRDVEHFFRGYGKLSDVIMKNGFGFVDFQDQRDADDAVHDLNGKELCGERVIL 67

  Fly   152 QVSTSRVRPKPGMGDPEQCYRCGRSGHWSKECPRLYGSAGGGREPPSPLSAGGYR--DRMYGRDP 214
            :.      |:..:|..|:     ||           ||...||||  ....||.|  ...|.|
Worm    68 EF------PRRKVGYNEE-----RS-----------GSGFRGREP--TFRKGGERQFSNRYSR-- 106

  Fly   215 YPPPPPPPPF---------------LRDRIM--------------------------DGFRD--- 235
                |....|               ::|.|.                          |..||
Worm   107 ----PCSTRFRLVIDNLSTRYSWQDIKDHIRKLGIEPTYSEAHKRNVNQAIVCFTSHDDLRDAMN 167

  Fly   236 ----YDYYDRRF---EDSRDLYERRYQTSRMRDFPP-----PPISRREPMPLPPTLSGSLRSCSV 288
                .|...|:.   :::||....|....|.|...|     ||..||.|        ||.||...
Worm   168 KLQGEDLNGRKLKCTDETRDRSRSRSPRRRSRSRSPTRSRSPPARRRSP--------GSDRSDRK 224

  Fly   289 SRGYDTMFSRRSPPPPRS-SNGMSRYGSPTPHGYEDFSRDAFDERMISSRGMRGPSPPGRRYAP 351
            ||....  .:||....|| |...||.|                     .|..|..|||.|..:|
Worm   225 SRSASP--KKRSDKRARSESKSRSRSG---------------------GRRSRSNSPPNRSPSP 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lark	NP_523957.1	RRM1_2_CoAA_like	8..73	CDD:409779
		RRM1_2_CoAA_like	87..152	CDD:409779	16/64 (25%)
		hnRNP-R-Q	<88..>258	CDD:273732	44/222 (20%)
rsp-2	NP_496441.1	RRM_SF	112..184	CDD:302621	8/71 (11%)
rsp-2	NP_496441.1	RRM1_SRSF4_like	3..71	CDD:240783	16/73 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910