DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lark and rsp-5

DIOPT Version :9

Sequence 1:	NP_523957.1	Gene:	lark / 38811	FlyBaseID:	FBgn0011640	Length:	352	Species:	Drosophila melanogaster
Sequence 2:	NP_495307.3	Gene:	rsp-5 / 174073	WormBaseID:	WBGene00004702	Length:	208	Species:	Caenorhabditis elegans

Alignment Length:	264	Identity:	60/264 - (22%)
Similarity:	89/264 - (33%)	Gaps:	69/264 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    87 KIFVGNLTDKTRAPEVRELFQKYGTVVECDIVRNYGFVHLDCVGDVQDAIKELNGRVVDGQPLKV 151
            ::::|.:....|..:|....:.||.:....:...:.||..:...|.:||..:|:|:.::|..:::
Worm     3 RLYLGKIPYNARERDVERFLKGYGKINNISMKYGFAFVDFEDSRDAEDACHDLDGKTMEGSSMRL 67

  Fly   152 QVSTSRVRPKPGMGDPEQCYRCGRSGHWSKECPRLYGSAGGGREPPSPLSAGGYRDRMYGRDPYP 216
            .|..:|.:|:            |...|             |.|.|           |...|.|..
Worm    68 VVEMARGKPR------------GNDRH-------------GSRSP-----------RRRSRSPRR 96

  Fly   217 PPPPPPPFLRDRIMDGFRDYDYYDRRFEDSRDLYERRYQTSRMRDFPPPPI--SRREPMPLPPTL 279
            ....||                  ||...|||....|...||.......|:  |||.
Worm    97 RSRTPP------------------RRRSRSRDRKRSRRSRSRSSSRSRSPVRESRRR-------- 135

  Fly   280 SGSLRSCSVSRGYDTMFSRRSPPPPRSSNGMSRYGSPTPHGYE---DFSRDAFDERMISSRGM-R 340
             ...||.|..|......||...|.|......:|.|||..:|.:   ..||.....|..|:|.: |
Worm   136 -SESRSPSPKRDLKREASRSRSPLPAKDRSRTRSGSPPKNGGDRKRSVSRGRSHSRDGSNRSVSR 199

  Fly   341 GPSP 344
            .|||
Worm   200 SPSP 203

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lark	NP_523957.1	RRM1_2_CoAA_like	8..73	CDD:409779
		RRM1_2_CoAA_like	87..152	CDD:409779	13/64 (20%)
		hnRNP-R-Q	<88..>258	CDD:273732	32/169 (19%)
rsp-5	NP_495307.3	RRM	<3..>77	CDD:223796	15/73 (21%)
rsp-5	NP_495307.3	RRM_SF	3..74	CDD:302621	14/70 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910