Protein Alignment lark and SRSF8

DIOPT Version :10

• Sequence 1: NP_523957.1
• Gene: lark / 38811
• FlyBaseID: FBgn0011640
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: NP_115285.1
• Gene: SRSF8 / 10929
• HGNCID: 16988
• Length: 282
• Species: Homo sapiens
• Alignment Length: 257
• Identity: 74/257 - (28%)
• Similarity: 98/257 - (38%)
• Gaps: 32/257 - (12%)

  Fly    90 VGNLTDKTRAPEVRELFQKYGTVVECDI--------VRNYGFVHLDCVGDVQDAIKELNGRVVDG 146
            |.|||.:|....:|.:|:|||.|.:..|        .|.:.||......|.|||...::|..:||
Human    18 VDNLTYRTSPDSLRRVFEKYGRVGDVYIPREPHTKAPRGFAFVRFHDRRDAQDAEAAMDGAELDG 82

  Fly   147 QPLKVQVST--SRVRPKPGMGDPEQCYRCG------RS-GHWSKECPRLYGSAGGGREPPSPLSA 202
            :.|:|||:.  .|..|:...|:|....|.|      || |..|:...|.:.|...|.......|.
Human    83 RELRVQVARYGRRDLPRSRQGEPRGRSRGGGYGRRSRSYGRRSRSPRRRHRSRSRGPSCSRSRSR 147

  Fly   203 GGYRDRMYGRDPYPPPP------PPPPFLRDRIMDGFRDYDYYDRRFEDSRDLYER--RYQTSRM 259
            ..||...|.|.||...|      ...|:.|.|    :|:..|....:..|.....|  ||.:||.
Human   148 SRYRGSRYSRSPYSRSPYSRSRYSRSPYSRSR----YRESRYGGSHYSSSGYSNSRYSRYHSSRS 208

  Fly   260 RDFPPPPISRREPMPLPPTLSGSLRSCSVSRGYDTMFS---RRSPPPPRSSNGMSRYGSPTP 318
            ........|.|.......:.:...:|.||||......|   .||||........||..|..|
Human   209 HSKSGSSTSSRSASTSKSSSARRSKSSSVSRSRSRSRSSSMTRSPPRVSKRKSKSRSRSKRP 270

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lark	NP_523957.1	RRM1_2_CoAA_like	8..73	CDD:409779
		RRM1_2_CoAA_like	87..152	CDD:409779	23/69 (33%)
		hnRNP-R-Q	<88..>258	CDD:273732	56/192 (29%)
SRSF8	NP_115285.1	RRM_SRSF2_SRSF8	16..88	CDD:409751	23/69 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	91..282		48/184 (26%)