Protein Alignment lark and SRSF10

DIOPT Version :10

• Sequence 1: NP_523957.1
• Gene: lark / 38811
• FlyBaseID: FBgn0011640
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: NP_473357.1
• Gene: SRSF10 / 10772
• HGNCID: 16713
• Length: 262
• Species: Homo sapiens
• Alignment Length: 283
• Identity: 69/283 - (24%)
• Similarity: 100/283 - (35%)
• Gaps: 84/283 - (29%)

  Fly    84 PTTKIFVGNLTDKTRAPEVRELFQKYGTVVECDI--------VRNYGFVHLDCVGDVQDAIKELN 140
            |.|.:||.|:.|.||:.::|..|.:||.:|:..:        .|.:.:|..:.|.|.:||:..|:
Human     8 PNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDALHNLD 72

  Fly   141 GRVVDGQPLKVQVSTSRVRPKPGMGDPEQCYRCGRSGHWSKECPRLYGSAGGGREPPSPLSAGGY 205
            .:.:.|:.:::|.                                    |.|.|:.|:.:.|
Human    73 RKWICGRQIEIQF------------------------------------AQGDRKTPNQMKA--- 98

  Fly   206 RDRMYGRDPYPPPPPPPPFLRDRIMDGFRDYDYYDRRFEDSRDLYERRYQTSRMRDFPPPPISRR 270
               ..||:.|.             ...:.|||.|.|....|   ||||...||..|:.    .||
Human    99 ---KEGRNVYS-------------SSRYDDYDRYRRSRSRS---YERRRSRSRSFDYN----YRR 140

  Fly   271 EPMPLPPTLSGSLRSCSVSRGYDTMFSRRSPPPPRS-SNGMSRYGSPTPHGYEDFSRDAFDERMI 334
            ...|.....:|..|. |.|...:..|..|:....|| ||..||..|......:..||    .|..
Human   141 SYSPRNSRPTGRPRR-SRSHSDNDRFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKSR----SRSA 200

  Fly   335 SSRGMRGPS--------PPGRRY 349
            |....||.|        ..|.||
Human   201 SHTKTRGTSKTDSKTHYKSGSRY 223

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lark	NP_523957.1	RRM1_2_CoAA_like	8..73	CDD:409779
		RRM1_2_CoAA_like	87..152	CDD:409779	19/72 (26%)
		hnRNP-R-Q	<88..>258	CDD:273732	38/177 (21%)
SRSF10	NP_473357.1	RRM_SF	5..99	CDD:473069	27/132 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	116..262		36/120 (30%)