Protein Alignment mrva and AZR1

DIOPT Version :10

• Sequence 1: NP_648103.1
• Gene: mrva / 38808
• FlyBaseID: FBgn0035763
• Length: 478
• Species: Drosophila melanogaster
• Sequence 2: NP_011740.3
• Gene: AZR1 / 853139
• SGDID: S000003456
• Length: 613
• Species: Saccharomyces cerevisiae
• Alignment Length: 557
• Identity: 112/557 - (20%)
• Similarity: 187/557 - (33%)
• Gaps: 203/557 - (36%)

  Fly    63 FGSYFCYDAPGALQNYFKKDLNLTSAQFTLIYSIYSWPNVVLCFVGGFLIDRLFGIRLGTIIYMM 127
            ||||                     ::...:::.||.||.:|..:.|.:...: |.:...:..::
Yeast    98 FGSY---------------------SEIGWLFTGYSLPNALLALIWGRIATPI-GFKETMLFAIV 140

  Fly   128 ILLVGQLIFACGGILDAFWMMILGRFIFGIGA----------------ES-----LAVAQNSYAV 171
            |..:|.||.|   :.::..|:|.||.|.|:|.                ||     :||...|:|:
Yeast   141 IFEIGSLISA---LANSMSMLIGGRVIAGVGGCGIQSLSFVIGSTLVEESQRGILIAVLSCSFAI 202

  Fly   172 LWFKGKELNMVF-----------------GLQLSVARF----GSTVNFWVMQPIYEYVSNF---- 211
            ....|..|..||                 ||...:..|    |.:.....|..|.::.|.|
Yeast   203 ASVVGPFLGGVFTSSVTWRWCFYVNLPIGGLAFFLFLFFYNPGLSTFQETMDNIRKFPSQFIEIV 267

  Fly   212 ---------YKGHTALG-----------------VVLLLATLTCVM---------------SMTC 235
                     .||.:.|.                 .|...|..||::               |:..
Yeast   268 RNVAYHLLKIKGFSKLNGWRKPFMELIFMYDIIEFVFCSAGFTCILLAFTFGGNRYAWNSASIII 332

  Fly   236 ALILGWMDKRAERILQRNNNPAGQIPKLTDVFS--------FKPPFWMVSI---ICVAYYVAIFP 289
            ..|:|.:......|......|...|.|.|..:.        .||..:.|:|   :..|.|::.|.
Yeast   333 LFIIGIVLVVLAGIYDFLVFPKFNIVKATPHYQPLMSWTNIKKPGIFTVNIALFLTCAGYISQFT 397

  Fly   290 FIALGQNFFVDRFGLSPAEANTVDSLVYLIAAVSSPVF-----GFIIDKLGRNV--TWVFTATLT 347
            :|.   .:|...:..|...|     .|:|:|.:.|.|.     |.|.||. |.:  ..|.::...
Yeast   398 YIV---QYFQLIYNDSAWRA-----AVHLVACIISTVVTAILCGAITDKT-RQIKPIIVISSIFG 453

  Fly   348 TIGAHALLTF----TQLTPYVGMIIM-GLSYSMLAASLWPLVALIIPEYQLG------------- 394
            .:|| .:||.    ...:.::|::|: |:::..||.|     :::..:.||.
Yeast   454 VVGA-GILTLLNNNANNSAHIGLLILPGVAFGGLAQS-----SMLASQIQLDKKSPTFRSDFVSI 512

  Fly   395 -TAYGFCQ------------------SIQNLGLAVITIVAGIIVD--------HSGGEHMWL--- 429
             |...||:                  :|:.|..|.|.:..|..||        :..|.|..|
Yeast   513 TTFNTFCKNLGQALGGVISNTVFSAAAIKKLTKANIQLPDGTTVDNLVIYRQTNFDGSHSKLGNI 577

  Fly   430 ------QLFFM--GWLTIALISTGVIWAYNNKNRGNL 458
                  .:|:|  |:..::||.  .::|.|.|...:|
Yeast   578 ISESLTDVFYMALGFYALSLIF--AVFASNKKVTASL 612

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mrva	NP_648103.1	MFS_MFSD1	55..450	CDD:340898	108/547 (20%)
AZR1	NP_011740.3	MFS_Azr1_MDR_like	83..540	CDD:341045	93/481 (19%)