Protein Alignment Rint1 and drp1

DIOPT Version :10

• Sequence 1: NP_648102.2
• Gene: Rint1 / 38807
• FlyBaseID: FBgn0035762
• Length: 724
• Species: Drosophila melanogaster
• Sequence 2: NP_595594.1
• Gene: drp1 / 2541081
• PomBaseID: SPBC691.02C
• Length: 678
• Species: Schizosaccharomyces pombe
• Alignment Length: 772
• Identity: 165/772 - (21%)
• Similarity: 280/772 - (36%)
• Gaps: 199/772 - (25%)

  Fly    46 QTLDYEDPQNVSCYKT--AFQCQQQVCE---------SIDFELEKLAHFEDKLKRKLKE------ 93
            |.:|:.|.:....||:  ..:.||:|.|         .|..|.||....||...|:..|
pombe     5 QLIDFIDSRTRHPYKSDEVEKFQQEVNELQLPDPNSLPILSEEEKRQAREDAAFRRSSEGLEDAW 69

  Fly    94 --------CQPVLEGVAEDLDKVRQLQRLQQYLLLVQDIQEISAALGNAINGKDEDKLVNIYLTL 150
                    ..|:.....|.|...:...:....|..|.:..:.|.........|||.::
pombe    70 LDSAIPADPTPIFRDTVELLCVYQSFVKKSASLDTVANFLDFSTDFSTLSTKKDETEI------- 127

  Fly   151 YEGNDCEHSVVGRLHAVQAQSLKSFAERTAIYWHKLLLKRLSSAFEAVLKSMRWAHLEQQALNYS 215
              ..||.|.:...|...:.:.:|.       .|...|.::|.:.|       .|     .|:| .
pombe   128 --APDCLHYIAELLFQKKEREVKE-------KWKNELTEKLKTLF-------NW-----PAIN-P 170

  Fly   216 SARDTAKAQLLAEYMFLIKSPAEERAPLQSITPSIVCQPINRVVQLLLAPYRQRFQFHFTGTRQT 280
            :.::::|.:   .:...::|       :||...|....|:  .:|:.:.||..:|::||...:||
pombe   171 NLKESSKFE---SFFGFVRS-------IQSFKDSETGLPL--FMQVYITPYVNQFRYHFMSQKQT 223

  Fly   281 NRLDKPEWFYTQILNWGKETHFFVGKTFQPAAIKAGKLDYNLRLE------------FIRGLVQL 333
            |.|.|||||:.           |:.|.|     ::.:..|.|..:            ||..|..:
pombe   224 NVLSKPEWFFE-----------FLLKVF-----RSNRSFYMLMRDIKFFPGVPPFFTFINLLNNV 272

  Fly   334 AIEKLAVDIEQIAQDQILFAHLLDETLAFESELRETFGYPASFPSAISVITQPMYLLRWISLEER 398
            |.|||.   ..|..|..| .||:.|||.:...|.:.|.|... |..|.:..|.....:|:.||.:
pombe   273 AKEKLT---HIIKYDDYL-VHLVHETLQYSVRLEQHFHYTQD-PLIIFLFEQNGTYDKWLGLETQ 332

  Fly   399 FCAEKMDDILQAETPFQLIDPNSFENDLKIP-KCADQFMRLLDAIKDRYYGLIQPGHQLQFLHLQ 462
            ....|::||..|...::|....|.:....:| |...:|..:::........|....:|..|
pombe   333 LSLTKLEDIKIASDAWELESDQSDDFSSAVPTKMTVRFRDMIETTFSVLQNLPSLDYQFNF---- 393

  Fly   463 LELIDSFRQRLVQLHSSGAVPSIPILNAINYLVMVLREWGENVHYLHLHAALAGPNATEINSVFE 527
                    .|.|||.        |::..:|:| ....|..|:...:||..:|    .|: .|.|:
pombe   394 --------WRSVQLK--------PMMQYVNWL-EAFYESHESSSSIHLPGSL----QTD-KSKFD 436

  Fly   528 HAVAELEHWAR-------------------------------------QLMRNLATKATNE---- 551
              :||:|...:                                     |:...|:|.....
pombe   437 --IAEVERMCKLYSNFKLLMDWLDDIEDEDVYIRIGHKMGSENYAAFYQVKPRLSTLTNGSFRMI 499

  Fly   552 MKAKSMSYR--------RDAWPTMPEQNSREPFILSPSGGEM--FQV-LVTLLHNLERELSANLF 605
            ::|.|.:.|        .|.| .:.||......:.:....|:  ||. |..::..|::.|..:..
pombe   500 LRAVSQTLRPLLDNYSDLDTW-VIKEQLPGAALLSTSVSAEIVGFQSRLKEIIALLQKLLIGSSQ 563

  Fly   606 TQTLRLIAHQIDDFMLESMVMNTKFSAAGAAQFNYDMTRNLFALFGQYTRRPELLFKRTHDACKL 670
            .:.:..|...::.:|:: :||..:||..|..||..| ...:...|..|   |.|.|:|.....:|
pombe   564 CEAIYQIGTLVESWMIK-IVMTHQFSVRGGVQFAMD-AMQIVLEFSDY---PLLKFERLMSTVEL 623

  Fly   671 LAAARG----TALLLLETLRGNQS-VEE--KTKPLRELHVLSMDSKQCIEVLERRMD 720
            |:...|    ...|::|..:.|.. ::|  |||.      :::..:..:.||.||:|
pombe   624 LSLESGENKLIKKLIIEINQKNYDFIDEFFKTKE------ITLSYEDALGVLYRRVD 674

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rint1	NP_648102.2	RINT1_TIP1	260..718	CDD:461309	118/529 (22%)
drp1	NP_595594.1	RINT1_TIP1	200..672	CDD:461309	118/534 (22%)