Protein Alignment Rint1 and rint1

DIOPT Version :10

• Sequence 1: NP_648102.2
• Gene: Rint1 / 38807
• FlyBaseID: FBgn0035762
• Length: 724
• Species: Drosophila melanogaster
• Sequence 2: XP_002933153.2
• Gene: rint1 / 100379743
• XenbaseID: XB-GENE-982860
• Length: 785
• Species: Xenopus tropicalis
• Alignment Length: 766
• Identity: 235/766 - (30%)
• Similarity: 383/766 - (50%)
• Gaps: 83/766 - (10%)

  Fly     7 EMELRIVARLNEEIGKDASQLHRASHL---VSHYKKHLQVLSQTLDYEDPQNVSCYKTAFQCQQQ 68
            |:.|.:...:.:|||.|...|...|:|   :...||||:....|:..|.|:.:   :.|.:..:.
 Frog    34 EIPLYVCEFVEKEIGNDFKSLKNVSNLIETIKEEKKHLEEQVLTVSSEAPKRI---QAALKNAED 95

  Fly    69 VCESIDFELEKLAHFEDKLKRKLKECQPVLEGVAEDLDKVRQLQRLQQYLLLVQDIQEISAALGN 133
            ...|:|..|:|.....:.:...|:|..|.::.:...::::.:::|...||..:..|:|:|..:..
 Frog    96 SKTSLDLLLQKEIVVTESISVHLEEAAPWMDDLGVLINQMEEVERYLSYLKWISQIEELSDNIQQ 160

  Fly   134 AINGKDEDKLVNIYLTLYE------GNDCEHSVVGRLHAVQAQSLKSFAERTAIYWHKLLLKRLS 192
            .:...|..:..:..:.:.|      .:.|.|             |.:|.:.|..:|||:|..:|:
 Frog   161 HLMTNDVAEAASTLVCMAELAIKLQESSCSH-------------LLTFIKSTVQFWHKILKDKLT 212

  Fly   193 SAFEAVLKSMRWAHLEQQALNYSSA-------------RDTAKAQLLAEYMF--LIKSPAEERAP 242
            |.||.||.::.|..: ...|:.:||             .:|..:|||.....  ||..|.|  .|
 Frog   213 SDFEEVLNNLHWPFI-GPLLSSASAPPVSATVAEIYTNLETLFSQLLKLQTSDELITKPKE--MP 274

  Fly   243 LQSITPSIVCQPINRVVQLLLAPYRQRFQFHFTGTRQTNRLDKPEWFYTQILNW-GKETHFFVGK 306
            .:...|::  .||...:|::|:|.::||::||||.:|||.|.||||:.||:|.| |..|. |:.:
 Frog   275 EKYSLPAL--PPIMLPIQIMLSPLQKRFRYHFTGNKQTNVLSKPEWYLTQVLMWIGNHTK-FLQE 336

  Fly   307 TFQPAAIKAGKLDYNLRLEFIRGLVQLAIEKLAVDIEQIAQDQILFAHLLDETLAFESELRETFG 371
            ..||...|:|. ..|..|||.||||.|.:|||||||..:..|.|||.||:||.|.|:.||..:.|
 Frog   337 RIQPILTKSGS-SVNAHLEFTRGLVMLVLEKLAVDIPLLLYDDILFCHLVDEVLLFQRELYTSHG 400

  Fly   372 YPASFPSAISVITQPMYLLRWISLEERFCAEKMDDILQAETPF--QLIDPNSFENDLKIPKCADQ 434
            ||::.|:.:.::::.....||:::|.:...||||.:|.||..:  |..|.:..: ::|:|..|:.
 Frog   401 YPSNLPNCMHILSEETCFQRWLTVERKLALEKMDSMLSAEAAWTSQYKDISDVD-EMKVPDSAET 464

  Fly   435 FMRLLDAIKDRYYGLIQPGHQLQFLHLQLELIDSFRQRLVQLHSSGAVPSI-----PILNAINYL 494
            ||.||..|.|||..|.....:|:||.||.:|:|.||.||.|:....:...:     .||||:||:
 Frog   465 FMTLLLVITDRYRNLPTASRKLKFLELQKDLVDDFRIRLTQVMKEESRDPLGFRYCAILNAVNYI 529

  Fly   495 VMVLREWGENVHYLHLHAALAGPNATEIN---------------SVFEHAVAELEHWARQLMRNL 544
            ..||.:|.:||.:|.|..| |....|::|               |||:..:..||.....::...
 Frog   530 ATVLGDWADNVFFLQLQQA-ALEICTDLNASSKLQLGQLASMEISVFDDLINLLERLKNDMLSRQ 593

  Fly   545 ATKATNEMKAKSMSYRRDAWPTMPEQNSREPFILSPSGGEMFQVLVTLLHNLERELSANLFTQTL 609
            ......|:|..:..|:::.|.::|.|:.:....||.:...|...|...|..:|::|...||....
 Frog   594 VEHVFKEVKEAARMYKKERWLSLPSQSEQAVMSLSSTACPMLLALRDRLLQMEQQLCHALFKTVW 658

  Fly   610 RLIAHQIDDFMLESMVMNTKFSAAGAAQFNYDMTRNLFALFGQYTRRPELLFKRTHDACKLLAAA 674
            :::|.::|.|:.:.:::...|:..||||..:||:||||.||..|.:|||..||...:||.:|...
 Frog   659 QMLAEKLDLFIYQDIILANHFNEGGAAQLQFDMSRNLFPLFSHYCKRPENYFKHVKEACIILNLN 723

  Fly   675 RGTALLLLETLR----------GNQSVEEKTKPLRELHVLSMDSKQCIEVL 715
            .|.||||.:.|:          .|..:...|..|.||.:..: :.|.:|:|
 Frog   724 VGPALLLKDVLQTASESMNACSSNDKLPSSTAALNELGIYKL-APQDVEIL 773

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rint1	NP_648102.2	RINT1_TIP1	260..718	CDD:461309	172/489 (35%)
rint1	XP_002933153.2	CLb	42..>169	CDD:128345	29/129 (22%)
		RINT1_TIP1	287..777	CDD:461309	172/492 (35%)