Sequence 1: | NP_648101.1 | Gene: | RhoGEF4 / 38806 | FlyBaseID: | FBgn0035761 | Length: | 647 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_005426.2 | Gene: | ARHGEF5 / 7984 | HGNCID: | 13209 | Length: | 1597 | Species: | Homo sapiens |
Alignment Length: | 391 | Identity: | 99/391 - (25%) |
---|---|---|---|
Similarity: | 164/391 - (41%) | Gaps: | 91/391 - (23%) |
- Green bases have known domain annotations that are detailed below.
Fly 73 QAIQEI----ISSEKSYLEQLELLMNFFVRPLKEQAIIDCSNHTLLFGQIEMIHNLNGEFLRELE 133
Fly 134 ANMEN------VAHAFLKMAP-FFKLYSVYAFD--YRGALFIIQDLISKNPVFRKFLEQTESRPE 189
Fly 190 VQR-KLNSLMIVPIQRVPRYKLLLEQVLLYTSPADADYKLLKESVKEIEATASH------INTC- 246
Fly 247 --VEEQEITQYLIHLQNSLVNRTP--NIVKPSRRVIKEGVL------------QKITHKGTEIKR 295
Fly 296 Y--CVLMS-----DIFMYCKMIKERAPNTVVENSLECCCIFPLKKCKVYEMLPGNFK------LT 347
Fly 348 CQSDG----IIFGSGDVQLSRTWVGFI---RDAIDL-------HVQCRKTLRKDSSKRTPIRKKD 398
Fly 399 M 399 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
RhoGEF4 | NP_648101.1 | RhoGEF | 74..244 | CDD:279015 | 62/189 (33%) |
PH-like | 269..>311 | CDD:302622 | 10/60 (17%) | ||
PH | 277..374 | CDD:278594 | 20/128 (16%) | ||
ARHGEF5 | NP_005426.2 | ARHGEF5_35 | 1..478 | CDD:292081 | |
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 138..246 | ||||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 258..455 | ||||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 467..1072 | ||||
RhoGEF | 1178..1356 | CDD:279015 | 61/188 (32%) | ||
PH_ephexin | 1378..1504 | CDD:269929 | 22/141 (16%) | ||
PH | 1391..1497 | CDD:278594 | 19/121 (16%) | ||
SH3_ARHGEF5_19 | 1514..1568 | CDD:212873 | 5/23 (22%) | ||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_COG5422 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
2 | 1.810 |