Sequence 1: | NP_648101.1 | Gene: | RhoGEF4 / 38806 | FlyBaseID: | FBgn0035761 | Length: | 647 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_001229658.1 | Gene: | ARHGEF38 / 54848 | HGNCID: | 25968 | Length: | 777 | Species: | Homo sapiens |
Alignment Length: | 749 | Identity: | 154/749 - (20%) |
---|---|---|---|
Similarity: | 267/749 - (35%) | Gaps: | 252/749 - (33%) |
- Green bases have known domain annotations that are detailed below.
Fly 26 ELRQVLQERNLLTAKSRRKVCSMLDSNNSSPIGSPNPDAGKRLGFRRQ-AIQEIISSEKSYLEQL 89
Fly 90 ELLMNFFVRPLKEQAI--IDCSNHTLLFGQIEMIHNLNGEFL-------RELEANMENVAHAFLK 145
Fly 146 M-APFFKLYSVYAFDYRGALFIIQDLISKNPVFRKFLE----------QTESRPEVQRKLNSLMI 199
Fly 200 VPIQRVPRYKLLLEQVLLYTSPADADYKLLKESVKEIEATASHINTCVEEQEITQYLIHLQN--- 261
Fly 262 -SLVNRTP-----NIVKPSRRVIKEGVLQKITHKGTEIK------------------RYCVLMSD 302
Fly 303 IFMYCKMIKERAP----------------------NTVVENSLECCCIF----------PLKKCK 335
Fly 336 VYEMLPGNFKLTCQSDGIIFGSGDVQLSRTWVGFIRDAIDLHVQCRKTLRKDSSKRTPIRKKDMK 400
Fly 401 KFGADYV-----LSPNKRK------CEYDTVFRNKNR----------------STDSE------E 432
Fly 433 ETEDSACFSRKRKVASGILRAPNGNPMGKASSSSSSSVSMKRVAPPPPAPPPPPAVQMRHQPG-- 495
Fly 496 RPGELATASKENRISKLYK-------------KIAAGDKVANVRGILKRSNVPAPNNDHDPSYGF 547
Fly 548 ASRY----SDSKSYFRAHNVDNTIPTFVKREDLFNGDNMFPVHLKSHEEICTPPQKKRVKFDDTL 608
Fly 609 DAVSPVLVEKPFAFS---------SESSSALKPT 633 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
RhoGEF4 | NP_648101.1 | RhoGEF | 74..244 | CDD:279015 | 51/189 (27%) |
PH-like | 269..>311 | CDD:302622 | 12/59 (20%) | ||
PH | 277..374 | CDD:278594 | 21/146 (14%) | ||
ARHGEF38 | NP_001229658.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 35..72 | 6/14 (43%) | |
RhoGEF | 98..284 | CDD:279015 | 52/190 (27%) | ||
BAR_DNMBP | 336..522 | CDD:153273 | 30/212 (14%) | ||
SH3 | 586..642 | CDD:302595 | 13/69 (19%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 673..694 | 5/20 (25%) | |||
SH3_DNMBP_C2 | 717..773 | CDD:213017 | |||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 0 | 0.000 | Not matched by this tool. | |||
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
1 | 0.910 |