| Sequence 1: | NP_648101.1 | Gene: | RhoGEF4 / 38806 | FlyBaseID: | FBgn0035761 | Length: | 647 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_598435.1 | Gene: | Arhgef5 / 54324 | MGIID: | 1858952 | Length: | 1581 | Species: | Mus musculus |
| Alignment Length: | 459 | Identity: | 108/459 - (23%) |
|---|---|---|---|
| Similarity: | 185/459 - (40%) | Gaps: | 119/459 - (25%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 25 RELRQVLQERNLLTAKSRRKVCSMLDS--------------------NNSSPIGSPNPDAGKRLG 69
Fly 70 FRRQAIQEIISSEKSYLEQLELLMNFFVRPLKEQAIIDCSNHTLLFGQIEMIHNLNGEFLRELEA 134
Fly 135 NMENVAHAFL-------KMAPFFKLYSVYAFD--YRGALFIIQDLISKNPVFRKFLEQTESRPEV 190
Fly 191 QR-KLNSLMIVPIQRVPRYKLLLEQVLLYTSPADADYKLLKESVKEIEATASH---------INT 245
Fly 246 CVEEQEITQYLIHLQNSLVNRTP--NIVKPSRRVIKEGVL------------QKITHKGTEIKRY 296
Fly 297 --CVLMS-----DIFMYCKMIKERAPNTVVENSLECCCIFPLKKC--KVYEMLPGNFKL----TC 348
Fly 349 QSDGIIFGSGDVQLSRT--------WVGFI---RDAIDL-------HVQCRKTLRKDSSKRTPIR 395
Fly 396 KKDM 399 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| RhoGEF4 | NP_648101.1 | RhoGEF | 74..244 | CDD:279015 | 59/188 (31%) |
| PH-like | 269..>311 | CDD:302622 | 11/60 (18%) | ||
| PH | 277..374 | CDD:278594 | 23/132 (17%) | ||
| Arhgef5 | NP_598435.1 | ARHGEF5_35 | 1..477 | CDD:373847 | |
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 25..54 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 159..274 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 316..643 | ||||
| PHA03247 | <398..949 | CDD:223021 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 659..700 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 741..810 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 829..1051 | ||||
| RhoGEF | 1164..1340 | CDD:366202 | 58/186 (31%) | ||
| PH_ephexin | 1362..1488 | CDD:269929 | 25/145 (17%) | ||
| SH3_ARHGEF5_19 | 1498..1552 | CDD:212873 | 5/23 (22%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG5422 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||