| Sequence 1: | NP_648101.1 | Gene: | RhoGEF4 / 38806 | FlyBaseID: | FBgn0035761 | Length: | 647 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | XP_005158835.1 | Gene: | itsn2b / 445153 | ZFINID: | ZDB-GENE-050309-102 | Length: | 1837 | Species: | Danio rerio |
| Alignment Length: | 682 | Identity: | 126/682 - (18%) |
|---|---|---|---|
| Similarity: | 234/682 - (34%) | Gaps: | 245/682 - (35%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 5 RQKGY----------GNGFIHSPQTPLSFSRELRQVLQERNLLTAK------SRRKVCSMLDSNN 53
Fly 54 -----------------------------------SSPIGSPNPDAGKRLGFRRQAIQEIISSEK 83
Fly 84 SYLEQLELLMNFFVRPLKE----------------QAIIDCSNHTL-------LFGQIEMIHNLN 125
Fly 126 GEFLRELEANMENVAHAFLKMAPFFKLYSVYAFDYRGALFIIQDLISKNPVFRKFLEQ--TESRP 188
Fly 189 EVQRKLNSLMIVPIQRVPRYKLLLEQVLLYTSPADADYKLLKESVKEIEATASHINTCVEEQEIT 253
Fly 254 QYL----IHLQ------NSLVNRTPNIVKPSRRVIKEGVLQKITHKGTEIKR------YCVLMSD 302
Fly 303 IFMYCKMIKERAPNTVVENSLECCCIFPLKKCKVYEMLPGNFKLTCQSDGIIFGSGDVQLSRTWV 367
Fly 368 GFIRDAIDLHVQCRKTLRKDSSKRTPIRKKDMKKFGADYVLSPNKRKCEYDTVFRNKNRSTDSEE 432
Fly 433 ETEDSACFSRKRKVAS-GIL-------------RAPNGNPMGKASSSSSSSVSMKRVAPPPPAPP 483
Fly 484 PPPAVQMRHQPGRPGELATASKENRISKLYKKIAAGDKVANVRGILKRSNVPAPNNDHDPSYGFA 548
Fly 549 SRYSDSKSYFRAHNVDNTIPTFVKREDLFNGD 580 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| RhoGEF4 | NP_648101.1 | RhoGEF | 74..244 | CDD:279015 | 46/194 (24%) |
| PH-like | 269..>311 | CDD:302622 | 9/47 (19%) | ||
| PH | 277..374 | CDD:278594 | 14/102 (14%) | ||
| itsn2b | XP_005158835.1 | EH | 7..99 | CDD:197477 | |
| EH | 19..83 | CDD:238009 | |||
| Amelogenin | <80..183 | CDD:197891 | |||
| EH | 232..327 | CDD:197477 | |||
| EH | 243..308 | CDD:238009 | |||
| TAF4 | <453..592 | CDD:296797 | |||
| DUF4349 | <559..691 | CDD:305044 | |||
| SH3 | 936..992 | CDD:302595 | |||
| SH3 | 1051..1102 | CDD:302595 | |||
| SH3_Intersectin_3 | 1126..1177 | CDD:212772 | |||
| SH3_Intersectin2_4 | 1198..1256 | CDD:212927 | 4/12 (33%) | ||
| SH3_Intersectin2_5 | 1271..1324 | CDD:212929 | 8/52 (15%) | ||
| RhoGEF | 1355..1535 | CDD:279015 | 46/194 (24%) | ||
| PH_ITSN | 1562..1692 | CDD:270084 | 32/200 (16%) | ||
| PH | 1576..1684 | CDD:278594 | 26/168 (15%) | ||
| C2_Intersectin | 1695..1829 | CDD:176021 | 19/135 (14%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG5422 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| ZFIN | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||