Sequence 1: | NP_648101.1 | Gene: | RhoGEF4 / 38806 | FlyBaseID: | FBgn0035761 | Length: | 647 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_001238891.1 | Gene: | ARHGEF26 / 26084 | HGNCID: | 24490 | Length: | 871 | Species: | Homo sapiens |
Alignment Length: | 324 | Identity: | 79/324 - (24%) |
---|---|---|---|
Similarity: | 133/324 - (41%) | Gaps: | 48/324 - (14%) |
- Green bases have known domain annotations that are detailed below.
Fly 24 SRELRQVLQERNLLTAKSRRKVCSMLDSNNSSPIGSPNPDAGKRLGF----------RRQAIQEI 78
Fly 79 ISSEKSYLEQLELLMNFFVRPLKEQAIIDCSNHTLLFGQIEMIHNLNGEFLRELEANMEN----- 138
Fly 139 ------VAHAFLKMAPFFKLYSVYAFDYRGALFIIQDLISKNPVFRKFLEQTESRPEVQR-KLNS 196
Fly 197 LMIVPIQRVPRYKLLLEQVLLYTSPADADYKLLKESVKEIEATASHINTCVEEQEITQ--YLIHL 259
Fly 260 QNSLVNRTPNIVKPSRRVIKEGVLQK-------ITHKGTEIKRYCVLMSDIFMYCKMIKERAPN 316 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
RhoGEF4 | NP_648101.1 | RhoGEF | 74..244 | CDD:279015 | 49/181 (27%) |
PH-like | 269..>311 | CDD:302622 | 10/48 (21%) | ||
PH | 277..374 | CDD:278594 | 9/47 (19%) | ||
ARHGEF26 | NP_001238891.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..49 | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 86..233 | ||||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 288..310 | ||||
RhoGEF | 443..622 | CDD:279015 | 49/182 (27%) | ||
PH_ephexin | 643..781 | CDD:269929 | 12/60 (20%) | ||
SH3_ARHGEF16_26 | 793..847 | CDD:212871 | |||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_COG5422 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
2 | 1.810 |