Sequence 1: | NP_648101.1 | Gene: | RhoGEF4 / 38806 | FlyBaseID: | FBgn0035761 | Length: | 647 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_694945.2 | Gene: | ARHGEF19 / 128272 | HGNCID: | 26604 | Length: | 802 | Species: | Homo sapiens |
Alignment Length: | 360 | Identity: | 80/360 - (22%) |
---|---|---|---|
Similarity: | 148/360 - (41%) | Gaps: | 63/360 - (17%) |
- Green bases have known domain annotations that are detailed below.
Fly 11 NGFIHSPQTPLSFSRELRQVLQER-------------------NLLTAKSRRKVCSMLDSNNSSP 56
Fly 57 IGSPNPDAG-----KRLGFR----RQAIQEIISSEKSYLEQLELLMNFFVRPLKEQAIIDCSNHT 112
Fly 113 LLFGQIEMIHNLNGEFLRELEANME------NVAHAFLKMAPFF-KLYSVYAFDYRGALFIIQDL 170
Fly 171 ISKNPVFRKFLEQTESRPEVQR-KLNSLMIVPIQRVPRYKLLLEQVLLYTSPADADYKLLKESVK 234
Fly 235 EIEATASHINTCVEEQEITQYLIHLQNSL--VNRTPNIVKPSRRVIKEGVL-------------Q 284
Fly 285 KITHKGTEIKRY--CVLMS--------DIFMYCKM 309 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
RhoGEF4 | NP_648101.1 | RhoGEF | 74..244 | CDD:279015 | 45/177 (25%) |
PH-like | 269..>311 | CDD:302622 | 11/64 (17%) | ||
PH | 277..374 | CDD:278594 | 10/56 (18%) | ||
ARHGEF19 | NP_694945.2 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..21 | ||
Herpes_ICP4_C | 10..>353 | CDD:332854 | 12/61 (20%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 84..138 | ||||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 171..190 | ||||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 222..283 | ||||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 306..342 | 7/35 (20%) | |||
RhoGEF | 382..558 | CDD:306973 | 44/175 (25%) | ||
PH_ephexin | 580..706 | CDD:269929 | 11/69 (16%) | ||
SH3_ARHGEF5_19 | 719..773 | CDD:212873 | |||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_COG5422 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
2 | 1.810 |