DRSC - DRSC Integrative Ortholog Prediction Tool

DRSC/TRiP Functional Genomics Resources

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Protein Alignment RhoGEF4 and fgd4

DIOPT Version :10

Sequence 1:	NP_648101.1	Gene:	RhoGEF4 / 38806	FlyBaseID:	FBgn0035761	Length:	647	Species:	Drosophila melanogaster
Sequence 2:	XP_031754365.1	Gene:	fgd4 / 100038050	XenbaseID:	XB-GENE-493422	Length:	895	Species:	Xenopus tropicalis

Alignment Length:	44	Identity:	9/44 - (20%)
Similarity:	19/44 - (43%)	Gaps:	1/44 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   106 YNFKDIGFAPYGEDWRTMRKLSVVELFSSKKLQSFRYIREEEND 149
            :.|||:......|:|..:...... |:....|:::|.:...:.|
Frog     8 FTFKDVAIEFSQEEWECLDPAQRA-LYRDVMLENYRNLLSLDED 50

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RhoGEF4	NP_648101.1	RhoGEF	74..244	CDD:459876	9/44 (20%)
		PH-like	269..>311	CDD:473070
		PH	277..374	CDD:459697
fgd4	XP_031754365.1	PspC_subgroup_2	<85..349	CDD:468202
		RhoGEF	339..522	CDD:238091
		PH1_FDG4	554..647	CDD:275434
		FYVE_FGD1_2_4	686..750	CDD:277280
		PH2_FGD1-4	770..872	CDD:270056
Blue background indicates that the domain is not in the aligned region.

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