Protein Alignment MED4 and mdt-4

DIOPT Version :9

• Sequence 1: NP_648094.1
• Gene: MED4 / 38799
• FlyBaseID: FBgn0035754
• Length: 258
• Species: Drosophila melanogaster
• Sequence 2: NP_494905.2
• Gene: mdt-4 / 173852
• WormBaseID: WBGene00007012
• Length: 334
• Species: Caenorhabditis elegans
• Alignment Length: 328
• Identity: 103/328 - (31%)
• Similarity: 145/328 - (44%)
• Gaps: 87/328 - (26%)

  Fly     6 STKERLLLLIDDIEMIAKELIEQAHQKISSTEL------VDLLDLLVAKDEEFRKMLELAEEQAK 64
            |.::.||...||:|.|.|.:::....:..|..|      .:::.|..:|.:..:.:|:...|..:
 Worm     8 SLRDLLLESADDLEHIVKMIVDTLINRDKSVMLKNGETVTNIIKLFDSKQDSIKTLLKRVPEFQE 72

  Fly    65 VEEAMDQLRAKVEVHDREIQKLQKSLKDAELILSTAIFQARQKLASINQANKRPVSSEELIKYAH 129
            .|:.:..|.|.||..|..||:|:.:||..|:.|:.:.|.|.|||..:.:|..|||:||.|||.||
 Worm    73 REQLIRTLEAHVEKRDEVIQQLETNLKSCEVALTRSCFHANQKLKQMKEAELRPVNSEMLIKLAH 137

  Fly   130 RISSANAVSAPLTWCIGDLRRPYPTDIEMRNG--------------LLGK-----------SEQN 169
            :||..|:|||||||.:||..||:|.:.|.|.|              |.||           |..:
 Worm   138 QISKHNSVSAPLTWQMGDPSRPFPQEHEFRAGHLLNSKVQSTGPQLLPGKNVAQRPLITSPSASS 202

  Fly   170 INGGTVTHQNSGMPSEQQRTLSGSAGSGSGS---GAGGEVPNAFQ---------NQFNWNLGELH 222
            .||||...:..|.|      |..||.:|..|   |.|.:.|...|         |:..|
 Worm   203 SNGGTAPIRTVGTP------LINSAPTGDFSPRTGFGTDEPPPIQQQVLRGATPNEKQW------ 255

  Fly   223 MTMGASGNT------------------VALE-----------TRAQD--DVEVMSTDSSSSS-SS 255
            ...|.||.|                  |.|:           .:.||  |||.||:|||:|| ||
 Worm   256 QNPGVSGATSTQSPYNRVSQSPSSSPNVKLKITGLPNRPGGIDQVQDVRDVEQMSSDSSNSSDSS 320

  Fly   256 DSQ 258
            |.:
 Worm   321 DDE 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MED4	NP_648094.1	Med4	47..189	CDD:287038	60/166 (36%)
mdt-4	NP_494905.2	Med4	47..247	CDD:287038	70/205 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156789
Domainoid	1	1.000	100	1.000	Domainoid score	I4423
eggNOG	1	0.900	-	-		E1_KOG4552
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	108	1.000	Inparanoid score	I3490
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1333917at2759
OrthoFinder	1	1.000	-	-		FOG0006646
OrthoInspector	1	1.000	-	-		oto17517
orthoMCL	1	0.900	-	-		OOG6_105627
Panther	1	1.100	-	-	LDO	PTHR13208
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2637
SonicParanoid	1	1.000	-	-		X4874
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.830