Protein Alignment Neos and NAB3

DIOPT Version :10

• Sequence 1: NP_523955.1
• Gene: Neos / 38795
• FlyBaseID: FBgn0024542
• Length: 371
• Species: Drosophila melanogaster
• Sequence 2: NP_015134.1
• Gene: NAB3 / 855911
• SGDID: S000006111
• Length: 802
• Species: Saccharomyces cerevisiae
• Alignment Length: 387
• Identity: 81/387 - (20%)
• Similarity: 151/387 - (39%)
• Gaps: 97/387 - (25%)

  Fly    19 KSRIFLGNLPV--CTREELVSICQPYGKVLGSMVQKNYGFVQFETEELANKAASALHKSTFKQNM 81
            |||:|:||||:  .::|:|..|..|||.::...::..:||:||:..:....|...     ..|.|
Yeast   329 KSRLFIGNLPLKNVSKEDLFRIFSPYGHIMQINIKNAFGFIQFDNPQSVRDAIEC-----ESQEM 388

  Fly    82 LTVRNASIKSKAANAIAKRNSNQGGQVTVQGGLVMSAA----AAAAGQPLIND------------ 130
            ...:...::..::|  |:...:.|...|......:|:|    ...:|. :.||
Yeast   389 NFGKKLILEVSSSN--ARPQFDHGDHGTNSSSTFISSAKRPFQTESGD-MYNDDNGAGYKKSRRH 450

  Fly   131 ---CEIIVQNRENTKYAEYIEERLKN-SSLRVDVLFPNEDVLLGKVLANISSRGCLYAVLVTPQH 191
               |.|.|:...:..||..:..|.:: :.|..|::|....:.|||::.:.:..|....|||...|
Yeast   451 TVSCNIFVKRTADRTYAIEVFNRFRDGTGLETDMIFLKPRMELGKLINDAAYNGVWGVVLVNKTH 515

  Fly   192 EEHNSITVNILY-GVPAEHR-----NMPLEDAITLIS-----------TDFRLKKQRD------- 232
                ::.|...| |...|.:     ::..:||:.:.:           ||:|....:.
Yeast   516 ----NVDVQTFYKGSQGETKFDEYISISADDAVAIFNNIKNNRNNSRPTDYRAMSHQQNIYGAPP 576

  Fly   233 -------AVVLPPSTSIHKGQRRHPQEMQ-----GLLERLADNH----------PLTAS--QYEV 273
                   ||..||.|:.::|....|.:.|     |.......:|          |:..|  :|:.
Yeast   577 LPVPNGPAVGPPPQTNYYQGYSMPPPQQQQQQPYGNYGMPPPSHDQGYGSQPPIPMNQSYGRYQT 641

  Fly   274 ILKYLEGEREEQLKREVGEANALAKLKAPDPE------IELQKKILSIMNKPAVTDVTSELM 329
            .:.  ....::|:.:..|...|     .|.|:      ::.|:.:.:|.|.|  .:|.|.|:
Yeast   642 SIP--PPPPQQQIPQGYGRYQA-----GPPPQPPSQTPMDQQQLLSAIQNLP--PNVVSNLL 694

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Neos	NP_523955.1	U2AF_lg	<19..149	CDD:273727	35/150 (23%)
		RRM_SF	20..78	CDD:473069	18/59 (31%)
NAB3	NP_015134.1	RRM_Nab3p	331..401	CDD:240788	19/74 (26%)