DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Neos and ncoa5

DIOPT Version :9

Sequence 1:	NP_001261502.1	Gene:	Neos / 38795	FlyBaseID:	FBgn0024542	Length:	371	Species:	Drosophila melanogaster
Sequence 2:	NP_988936.1	Gene:	ncoa5 / 394533	XenbaseID:	XB-GENE-5926600	Length:	625	Species:	Xenopus tropicalis

Alignment Length:	263	Identity:	75/263 - (28%)
Similarity:	128/263 - (48%)	Gaps:	63/263 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   123 AGQPLINDCEIIVQNRENTKYAEYIEERLKNSSLRVDVLFPNEDVLLGKVLANISSRGCLYAVLV 187
            |.:|:  ||.::|.|:::.:|||.:..::::..:.||::|.|.:|.|.:.|.:::..|..:|:::
Frog   214 AERPV--DCSVVVVNKQSKEYAESVGRKVRDLGMMVDLIFLNTEVSLTQALEDVTRGGSPFAIVI 276

  Fly   188 TPQHEEHNSITVNILYGVPAEHRNMPLEDAITLISTDF-RLK-----KQR------------DAV 234
            |.||:.|.|.|||||:|.|.|||||||.||:.||:.:: |.|     |:|            ||:
Frog   277 TQQHQVHRSCTVNILFGTPQEHRNMPLADAMVLIARNYERFKSETREKEREDIARQAAKMSADAI 341

  Fly   235 VLPP---STSIHKGQRRHPQEMQGLLERLADNHPLTASQYEVILKYLEGERE-----------EQ 285
            :...   :..:.:|..  |..:|.:|..||||..:|..:.:.::.||..::|           .|
Frog   342 LRERALLAEEVVRGPA--PPGIQAVLGLLADNRYVTVEEIDKVIHYLRDKKERLLGAPSDSLPSQ 404

  Fly   286 LKREVGEANALAKLK------APDPEI---------------------ELQKKILSIMNKPAVTD 323
            |.|....|..::.|.      |.:|.:                     |||.||||:.|..:...
Frog   405 LSRPSMGAAPVSSLDNQTSGLANNPALQMTQTISSASPAGQSVNTSQQELQAKILSLFNSGSAVG 469

  Fly   324 VTS 326
            .:|
Frog   470 ASS 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Neos	NP_001261502.1	U2AF_lg	<19..149	CDD:273727	9/25 (36%)
Neos	NP_001261502.1	RRM_SF	20..78	CDD:388407
ncoa5	NP_988936.1	PRK12678	<5..>152	CDD:237171
ncoa5	NP_988936.1	dermokine	<395..>589	CDD:416092	16/78 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D421126at33208
OrthoFinder	1	1.000	-	-		FOG0006056
OrthoInspector	1	1.000	-	-		otm47964
Panther	1	1.100	-	-	LDO	PTHR23295
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5288
SonicParanoid	1	1.000	-	-		X5759
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.050