Protein Alignment KMT5A and PR-Set7

DIOPT Version :9

• Sequence 1: NP_065115.3
• Gene: KMT5A / 387893
• HGNCID: 29489
• Length: 352
• Species: Homo sapiens
• Sequence 2: NP_001247100.1
• Gene: PR-Set7 / 41743
• FlyBaseID: FBgn0011474
• Length: 691
• Species: Drosophila melanogaster
• Alignment Length: 332
• Identity: 118/332 - (35%)
• Similarity: 167/332 - (50%)
• Gaps: 58/332 - (17%)

Human    77 THHEVKCQG------KPLAGIY----------RKREEKRNAGNAVRSAMKSEEQKIKDARKGPLV 125
            |.|.:.|..      |...||.          ||...|.....|..:|.||..:..:...:.|..
  Fly   358 TPHRILCPSPIKTALKVTGGICKVGSADPLSPRKSPRKLPTTTAAVAACKSRRRLNQPKPQAPYQ 422

Human   126 PF----PNQK-------------------------------SEAAEPPKTPPSSCDSTNAAIAKQ 155
            |.    |:|:                               :|..|.....|::.:|..|.:...
  Fly   423 PQLQKPPSQQQQQQQDDIVVVLDDDDDEGDDEDDVRALIKAAEERENQNKAPATANSNKAGMKTM 487

Human   156 ALKKPIKGKQAPRKKAQGK-------TQQNRKLTDFYPVRRSSRKSKAELQSEERKRIDELIESG 213
            ....|:|.|...:...:|:       |..||::|||:|||||.||:|..::.|..:.:::.:...
  Fly   488 LKPAPVKSKTKSKGPTKGQPPLPLAATNGNREMTDFFPVRRSVRKTKTAVKEEWMRGLEQAVLEE 552

Human   214 KEEGMKIDLIDGKGRGVIATKQFSRGDFVVEYHGDLIEITDAKKREALYAQDPSTGCYMYYFQYL 278
            :.:|:::....||||||:|.:.|.|.:|||||.||||.|.:|.:||..||.|.:.|||||||::.
  Fly   553 RCDGLQVRHFMGKGRGVVADRPFKRNEFVVEYVGDLISIGEAAEREKRYALDENAGCYMYYFKHK 617

Human   279 SKTYCVDATRETNRLGRLINHSKCGNCQTKLHDIDGVPHLILIASRDIAAGEELLYDYGDRSKAS 343
            |:.||:|||.:|.:||||||||:.||..||:..|...|||:|:|..||..||||.||||||||.|
  Fly   618 SQQYCIDATVDTGKLGRLINHSRAGNLMTKVVLIKQRPHLVLLAKDDIEPGEELTYDYGDRSKES 682

Human   344 IEAHPWL 350
            :..||||
  Fly   683 LLHHPWL 689

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KMT5A	NP_065115.3	SET_SETD8	200..339	CDD:380926	69/138 (50%)
PR-Set7	NP_001247100.1	SET	566..676	CDD:279228	63/109 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	138	1.000	Domainoid score	I4860
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4016
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003682
OrthoInspector	1	1.000	-	-		oto91512
orthoMCL	1	0.900	-	-		OOG6_105827
Panther	1	1.100	-	-	LDO	PTHR46167
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3321
SonicParanoid	1	1.000	-	-		X3045
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	9	8.890