DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Dscam2 and Ama

DIOPT Version :9

Sequence 1:NP_001261500.1 Gene:Dscam2 / 38788 FlyBaseID:FBgn0265296 Length:2101 Species:Drosophila melanogaster
Sequence 2:NP_731114.2 Gene:Ama / 40831 FlyBaseID:FBgn0000071 Length:341 Species:Drosophila melanogaster


Alignment Length:364 Identity:97/364 - (26%)
Similarity:145/364 - (39%) Gaps:68/364 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly   287 RVRLLGPILAIEAVTGEDSGVYKCTAGNVGGEASAELRLTVATPIQVEISPNVLSVHMGGTAEFR 351
            |:|||             .|:..|.|.::....||        |:..:||.:|:: .:|.:.||.
  Fly    11 RLRLL-------------IGLIFCLAISLDSVLSA--------PVISQISKDVVA-SVGDSVEFN 53

  Fly   352 CLV-----------------TSNGSPVGMQNILWYKDGR------QLPSSGRVEDTLVVPRVSRE 393
            |.|                 .:|...:.|:|||...|.|      :.|.:|....|..:..:...
  Fly    54 CTVEEVGQLSVSWAKRPSESDTNSVVLSMRNILSLPDQRYNVTVTEGPKTGSAIYTFRIQNIEVS 118

  Fly   394 NRGMYQCVVRRPEGDTFQATAELQLGDAPPVLLYSFIEQTL-QPGPAVSLKCSAAGNPTPQISWT 457
            :.|.|:|.|.....:.......||: ..|||:..:..:.|| ..|..:.|.|.|.|.|.|.|||.
  Fly   119 DMGPYECQVLVSATEKVTKKLSLQI-KTPPVIAENTPKSTLVTEGQNLELTCHANGFPKPTISWA 182

  Fly   458 LD-GFPLPSNGRFMIGQYITVHGDVISHVNISHVMVEDGGEYACIAENRAGRV-QHAARLNIYGL 520
            .: ...:|:.|..:        .:....:...|.|  |.|.|.|||:|..|:. :...|:.:...
  Fly   183 REHNAVMPAGGHLL--------AEPTLRIRSVHRM--DRGGYYCIAQNGEGQPDKRLIRVEVEFR 237

  Fly   521 PYIRL-IPKVTAVSGETLNLKCPVAGYPIEEIHWERGGRELPDDIRQRVQPDGS---LTISPVQK 581
            |.|.: .||:..:...:..|:|.|.|||...:.|.:.|..|.......|....|   .|.|.::.
  Fly   238 PQIAVQRPKIAQMVSHSAELECSVQGYPAPTVVWHKNGVPLQSSRHHEVANTASSSGTTTSVLRI 302

  Fly   582 NS----DSGVYTCWARNKQGHS-ARRSGEVTVIVPPKLS 615
            :|    |.|.|.|.|.||.||: ||.....|||..|.||
  Fly   303 DSVGEEDFGDYYCNATNKLGHADARLHLFQTVIPVPSLS 341

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Dscam2NP_001261500.1 Ig 51..127 CDD:299845
Ig 138..>203 CDD:299845
I-set 238..327 CDD:254352 9/39 (23%)
Ig 247..327 CDD:299845 9/39 (23%)
I-set 332..418 CDD:254352 23/108 (21%)
IGc2 344..407 CDD:197706 19/85 (22%)
IG_like 432..517 CDD:214653 25/87 (29%)
IGc2 436..507 CDD:197706 21/71 (30%)
I-set 521..610 CDD:254352 31/97 (32%)
IGc2 533..597 CDD:197706 21/70 (30%)
Ig 630..699 CDD:143165
IG_like 714..802 CDD:214653
Ig 725..802 CDD:299845
Ig 823..894 CDD:143165
FN3 906..1006 CDD:238020
FN3 1013..1111 CDD:238020
FN3 1119..1209 CDD:238020
FN3 1219..1313 CDD:238020
Ig 1336..1402 CDD:143165
FN3 1409..1498 CDD:238020
FN3 1515..1588 CDD:238020
AmaNP_731114.2 I-set 33..143 CDD:254352 24/110 (22%)
Ig 37..127 CDD:299845 21/90 (23%)
IG_like 154..234 CDD:214653 25/89 (28%)
IGc2 161..223 CDD:197706 21/71 (30%)
I-set 254..330 CDD:254352 25/75 (33%)
IGc2 254..322 CDD:197706 21/67 (31%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.900

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