Protein Alignment Dscam2 and ImpL2

DIOPT Version :10

• Sequence 1: NP_001261500.1
• Gene: Dscam2 / 38788
• FlyBaseID: FBgn0265296
• Length: 2101
• Species: Drosophila melanogaster
• Sequence 2: NP_728961.2
• Gene: ImpL2 / 38513
• FlyBaseID: FBgn0001257
• Length: 267
• Species: Drosophila melanogaster
• Alignment Length: 226
• Identity: 57/226 - (25%)
• Similarity: 77/226 - (34%)
• Gaps: 53/226 - (23%)

  Fly   404 RPEGDTFQATAELQLGDAPPVLLYSFIEQTLQPGPAVSLKCSAAGNPTPQISWTLDGFP------ 462
            :|....|:|. .|:....||..|..      ..|..:.:.|...|:..|.|.|.:...|
  Fly    47 KPRNRAFEAD-WLKFTKTPPTKLQQ------ADGATIEIVCEMMGSQVPSIQWVVGHLPRSELDD 104

  Fly   463 LPSNGRFMIGQYITVHGDVISHVNISHV---MVEDGGEYACIAEN-----RAGRVQHAARLNIYG 519
            |.||      |........|..|..||:   ::.:...|.|:...     .|..|.|..|.:
  Fly   105 LDSN------QVAEEAPSAIVRVRSSHIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSS--- 160

  Fly   520 LPYIRLIPKVT-----------------AVSGETLNLKCPVAGYPIEEIHW-ERGGRELPDDIRQ 566
                ||.|:.|                 .:.|..:.|.|.|...|..||.| ....:|:....|.
  Fly   161 ----RLTPEKTYPGAQKPRIIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRH 221

  Fly   567 RVQPDGSLTISPVQKNSDSGVYTCWARNKQG 597
            ||..:|.|.||.: |..|.|.|.|.|||..|
  Fly   222 RVLANGDLLISEI-KWEDMGNYKCIARNVVG 251

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dscam2	NP_001261500.1	Ig	30..128	CDD:472250
		Ig strand B	49..53	CDD:409353
		Ig strand C	62..66	CDD:409353
		Ig strand E	86..90	CDD:409353
		Ig strand F	106..111	CDD:409353
		Ig strand G	119..123	CDD:409353
		V-set	138..229	CDD:462230
		Ig	238..327	CDD:472250
		Ig strand B	255..259	CDD:409353
		Ig strand C	268..272	CDD:409353
		Ig strand E	293..297	CDD:409353
		Ig strand F	307..312	CDD:409353
		Ig strand G	320..323	CDD:409353
		Ig	330..418	CDD:472250	4/13 (31%)
		Ig strand B	348..352	CDD:409353
		Ig strand C	365..369	CDD:409353
		Ig strand E	383..387	CDD:409353
		Ig strand F	397..402	CDD:409353
		Ig strand G	411..414	CDD:409353	1/2 (50%)
		IgI_4_Dscam	422..517	CDD:409548	24/108 (22%)
		Ig strand A	422..425	CDD:409548	2/2 (100%)
		Ig strand A'	431..435	CDD:409548	0/3 (0%)
		Ig strand B	438..447	CDD:409548	1/8 (13%)
		Ig strand C	452..458	CDD:409548	3/5 (60%)
		Ig strand C'	460..463	CDD:409548	1/8 (13%)
		Ig strand D	468..476	CDD:409548	1/7 (14%)
		Ig strand E	480..489	CDD:409548	2/8 (25%)
		Ig strand F	496..504	CDD:409548	2/7 (29%)
		Ig strand G	507..517	CDD:409548	3/9 (33%)
		IgI_5_Dscam	521..608	CDD:409550	29/95 (31%)
		Ig strand A	521..523	CDD:409550	0/1 (0%)
		Ig strand A'	528..532	CDD:409550	1/20 (5%)
		Ig strand B	535..542	CDD:409550	1/6 (17%)
		Ig strand C	549..555	CDD:409550	3/6 (50%)
		Ig strand C'	556..558	CDD:409550	0/1 (0%)
		Ig strand D	565..569	CDD:409550	2/3 (67%)
		Ig strand E	572..578	CDD:409550	3/5 (60%)
		Ig strand F	586..594	CDD:409550	4/7 (57%)
		Ig strand G	598..608	CDD:409550	57/226 (25%)
		Ig	611..704	CDD:472250
		Ig strand B	630..634	CDD:409353
		Ig strand C	644..648	CDD:409353
		Ig strand E	670..674	CDD:409353
		Ig strand F	684..689	CDD:409353
		Ig strand G	697..700	CDD:409353
		IgI_7_Dscam	707..802	CDD:409546
		Ig strand A	707..711	CDD:409546
		Ig strand A'	716..720	CDD:409546
		Ig strand B	723..732	CDD:409546
		Ig strand C	738..744	CDD:409546
		Ig strand C'	750..753	CDD:409546
		Ig strand D	761..764	CDD:409546
		Ig strand E	767..773	CDD:409546
		Ig strand F	780..788	CDD:409546
		Ig strand G	793..802	CDD:409546
		Ig	806..892	CDD:472250
		Ig strand B	823..827	CDD:409353
		Ig strand C	836..840	CDD:409353
		Ig strand E	868..872	CDD:409353
		Ig strand F	882..887	CDD:409353
		FN3	<904..1195	CDD:442628
		FN3	906..1006	CDD:238020
		fn3	1221..1306	CDD:394996
		Ig	1336..1396	CDD:409353
Ig strand B	1336..1340	CDD:409353
Ig strand E	1371..1375	CDD:409353
Ig strand F	1385..1390	CDD:409353
FN3	<1407..>1606	CDD:442628
fn3	1408..1491	CDD:394996
ImpL2	NP_728961.2	PHA02785	<74..246	CDD:165149	45/185 (24%)
		Ig_3	173..248	CDD:464046	22/75 (29%)