DRSC/TRiP Functional Genomics Resources

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Protein Alignment Dscam2 and Iglon5

DIOPT Version :9

Sequence 1:NP_001261500.1 Gene:Dscam2 / 38788 FlyBaseID:FBgn0265296 Length:2101 Species:Drosophila melanogaster
Sequence 2:XP_218634.5 Gene:Iglon5 / 308557 RGDID:1305344 Length:336 Species:Rattus norvegicus


Alignment Length:310 Identity:72/310 - (23%)
Similarity:123/310 - (39%) Gaps:50/310 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly   627 GDRASLTCSVVKGDLPLT-INW---------RKDGRPIDPTQHMSVKQVDQYNSILVIENLGSDH 681
            ||.|:|:|.:   |..:| :.|         ..|....||...:.:...::::.::....||.: 
  Rat    47 GDNATLSCFI---DEHVTRVAWLNRSNILYAGNDRWTSDPRVRLLINTPEEFSILITQVGLGDE- 107

  Fly   682 TGNYSCVVRNSAAEVENSQALLVNVPPRW--IVEPVDANVERNRHIMLHCQAQGVPTPSIVWKKA 744
             |.|:|..:...........|:|:||.|.  |..||..|...|  :.|.|.|.|.|.|::.|::.
  Rat   108 -GLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVAVNEGGN--VNLLCLAVGRPEPTVTWRQL 169

  Fly   745 TGSKSGEYEEVRERPFTKLLGNGSLL-LQHVKEDREGFYLCQANNGIGTG-IGKVIQLKVNSSPY 807
            ....:.|               |.:| :..::..:.|.|.|..:||:.:. ..:.:.:.||..|.
  Rat   170 RDGFTSE---------------GEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPPT 219

  Fly   808 FSSTSRSVMVKKGDTALLQCAVSGDKPINIVWMRSGKNTLNPSTNYKISVKQEATPDGVSAELQI 872
            .:..: |.....|..|||:|......|.:..|.:..: .|:..:...:.|:.|.|    .:.|..
  Rat   220 ITDVT-SARTALGRAALLRCEAMAVPPADFQWYKDDR-LLSSGSAEGLKVQTERT----RSMLLF 278

  Fly   873 RTVDATDSGPYFCRASNLYGNDQQLVQL--------QVQEPPLPPSVLEA 914
            ..|.|...|.|.|||:|..|.....::|        ....||.|.::|.|
  Rat   279 ANVSARHYGNYTCRAANRLGASSASMRLLRPGSLENSAPRPPGPLTLLSA 328

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Dscam2NP_001261500.1 Ig 51..127 CDD:299845
Ig 138..>203 CDD:299845
I-set 238..327 CDD:254352
Ig 247..327 CDD:299845
I-set 332..418 CDD:254352
IGc2 344..407 CDD:197706
IG_like 432..517 CDD:214653
IGc2 436..507 CDD:197706
I-set 521..610 CDD:254352
IGc2 533..597 CDD:197706
Ig 630..699 CDD:143165 14/78 (18%)
IG_like 714..802 CDD:214653 19/89 (21%)
Ig 725..802 CDD:299845 15/78 (19%)
Ig 823..894 CDD:143165 20/70 (29%)
FN3 906..1006 CDD:238020 4/9 (44%)
FN3 1013..1111 CDD:238020
FN3 1119..1209 CDD:238020
FN3 1219..1313 CDD:238020
Ig 1336..1402 CDD:143165
FN3 1409..1498 CDD:238020
FN3 1515..1588 CDD:238020
Iglon5XP_218634.5 Ig 41..129 CDD:416386 17/86 (20%)
Ig strand A' 41..46 CDD:409353
Ig strand B 48..56 CDD:409353 4/7 (57%)
CDR1 56..60 CDD:409353 1/6 (17%)
FR2 61..68 CDD:409353 2/6 (33%)
Ig strand C 61..67 CDD:409353 2/5 (40%)
CDR2 69..79 CDD:409353 1/9 (11%)
Ig strand C' 71..74 CDD:409353 0/2 (0%)
Ig strand C' 76..79 CDD:409353 1/2 (50%)
FR3 80..115 CDD:409353 7/36 (19%)
Ig strand D 84..91 CDD:409353 0/6 (0%)
Ig strand E 94..100 CDD:409353 0/5 (0%)
Ig strand F 107..115 CDD:409353 3/9 (33%)
CDR3 116..120 CDD:409353 0/3 (0%)
Ig strand G 120..129 CDD:409353 1/8 (13%)
FR4 122..129 CDD:409353 1/6 (17%)
Ig strand A 132..137 CDD:409353 2/4 (50%)
Ig_3 134..199 CDD:404760 19/81 (23%)
Ig strand A' 140..145 CDD:409353 2/4 (50%)
Ig strand B 148..157 CDD:409353 3/10 (30%)
Ig strand C 163..167 CDD:409353 0/3 (0%)
Ig strand D 174..177 CDD:409353 1/17 (6%)
Ig strand E 178..183 CDD:409353 1/4 (25%)
Ig strand F 191..199 CDD:409353 3/7 (43%)
Ig_3 217..295 CDD:404760 21/83 (25%)
putative Ig strand A 218..224 CDD:409353 1/5 (20%)
Ig strand B 234..238 CDD:409353 3/3 (100%)
Ig strand C 247..251 CDD:409353 0/3 (0%)
Ig strand E 274..278 CDD:409353 1/3 (33%)
Ig strand F 288..293 CDD:409353 2/4 (50%)
Ig strand G 301..304 CDD:409353 0/2 (0%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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