DRSC/TRiP Functional Genomics Resources

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Protein Alignment Dscam2 and Lrit1

DIOPT Version :9

Sequence 1:NP_001261500.1 Gene:Dscam2 / 38788 FlyBaseID:FBgn0265296 Length:2101 Species:Drosophila melanogaster
Sequence 2:NP_666357.2 Gene:Lrit1 / 239037 MGIID:2385320 Length:624 Species:Mus musculus


Alignment Length:287 Identity:63/287 - (21%)
Similarity:93/287 - (32%) Gaps:101/287 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly   798 IQLKVNSSPYFSSTSRSVMVKKGDTALLQCAVSGDKPINIVWMRSGKNTLNPSTNYKISVKQEAT 862
            ::|:...||.......|::...|.|.||:|..:|.....:.|.|:....||.      :|.||.:
Mouse   247 LELRKCQSPELRPGVTSIISPLGSTVLLRCGATGIPGPEMSWRRANGRPLNG------TVHQEVS 305

  Fly   863 PDGVS-AELQIRTVDATDSGPYFCRASNLYGNDQQLVQLQVQEP--------------------- 905
            .||.| ..|.:..|...|||.|.|:|.|..|..:.|:.|.|.||                     
Mouse   306 SDGSSWTLLDLPVVSLFDSGDYICQAKNFLGASETLISLIVTEPQTSTGYSGIPGVLWARTGEGA 370

  Fly   906 --------------------------PLPPSV------------------------LEAAMISS- 919
                                      |..||:                        .||.|:.| 
Mouse   371 EAAAYNNKLVARHVPHMPEHVALATKPSMPSIKEELALQNFQMDVPGEFSREPSEHQEAQMVRSL 435

  Fly   920 -------RSVNIKWQPKTLGTGDVTKYIVEFREADHSLPPALFVDQWQQIEVKDPPHFNAMIENL 977
                   .||::.|  |....|:.|.:.|.:         |:|..:..:....:|...:..||.|
Mouse   436 KVVGDTYHSVSLVW--KAPQAGNTTAFSVLY---------AVFGHRDMRRMTVEPGKTSVTIEGL 489

  Fly   978 KPATRYAFRVIAEGSAGRSAPSQELIV 1004
            .|.|:|...|...|    ..|::|..|
Mouse   490 APKTKYVACVCVRG----LVPTKEQCV 512

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Dscam2NP_001261500.1 Ig 51..127 CDD:299845
Ig 138..>203 CDD:299845
I-set 238..327 CDD:254352
Ig 247..327 CDD:299845
I-set 332..418 CDD:254352
IGc2 344..407 CDD:197706
IG_like 432..517 CDD:214653
IGc2 436..507 CDD:197706
I-set 521..610 CDD:254352
IGc2 533..597 CDD:197706
Ig 630..699 CDD:143165
IG_like 714..802 CDD:214653 1/3 (33%)
Ig 725..802 CDD:299845 1/3 (33%)
Ig 823..894 CDD:143165 24/71 (34%)
FN3 906..1006 CDD:238020 28/131 (21%)
FN3 1013..1111 CDD:238020
FN3 1119..1209 CDD:238020
FN3 1219..1313 CDD:238020
Ig 1336..1402 CDD:143165
FN3 1409..1498 CDD:238020
FN3 1515..1588 CDD:238020
Lrit1NP_666357.2 LRRNT 23..61 CDD:214470
LRR 1 60..81
LRR_8 63..143 CDD:290566
leucine-rich repeat 64..84 CDD:275378
LRR 2 84..105
leucine-rich repeat 85..132 CDD:275378
LRR 3 108..129
LRR_8 131..>176 CDD:290566
LRR_4 131..172 CDD:289563
LRR 4 132..153
leucine-rich repeat 133..156 CDD:275378
LRR 5 156..177
leucine-rich repeat 157..180 CDD:275378
leucine-rich repeat 181..205 CDD:275378
TPKR_C2 201..>241 CDD:301599
Ig 258..346 CDD:299845 29/93 (31%)
IG_like 268..346 CDD:214653 28/83 (34%)
FN3 432..502 CDD:214495 18/80 (23%)
LRR 6 526..549
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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