DRSC/TRiP Functional Genomics Resources

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Protein Alignment Dscam2 and zig-3

DIOPT Version :10

Sequence 1:NP_001261500.1 Gene:Dscam2 / 38788 FlyBaseID:FBgn0265296 Length:2101 Species:Drosophila melanogaster
Sequence 2:NP_509336.1 Gene:zig-3 / 192088 WormBaseID:WBGene00006980 Length:251 Species:Caenorhabditis elegans


Alignment Length:241 Identity:62/241 - (25%)
Similarity:91/241 - (37%) Gaps:48/241 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly   682 TGNYSCVVRNSAAEVENSQALLVNVPPRWIVEPVDAN-VERNRHIMLHCQAQGVPTPSIVWKKAT 745
            :|.....|.|...|::::.  |...|...|:|.::.| |.....:.|.|.....||..|.|:|..
 Worm    19 SGEMRAAVSNLVREIDSTH--LTTKPSLKIIEGLEDNTVSTGESVTLRCDVLSTPTGVIYWEKDG 81

  Fly   746 GSKSGEYEEVRERPFTKLLG-------NGSLL---------LQHVKEDREGFYLCQANNGIGT-- 792
            ....|:.|   ...|.|:|.       :|.:.         |.|:     |.|.|.|.||..|  
 Worm    82 QRIQGDKE---LNVFEKVLNAMGPTVESGIITSSYQIPCANLHHI-----GSYKCVATNGHDTVE 138

  Fly   793 ------GIGKVIQLKV--NSSPYFSSTSRSVMVKKGDTALLQCAVSGDKPINIVWMRSGKNTLNP 849
                  ..|:.::.|.  .|:|..:.::.|....:.:.|.|.|  ..|:..|..||...|.....
 Worm   139 SSAKISVEGQTVKCKSTRRSAPVITMSTESRFELQDNAATLIC--RADRRANWNWMFEDKKIDFD 201

  Fly   850 STNYKISVKQEATPDGVSAELQIRTVDATDSGPYFCRASNLYGNDQ 895
            |..|      |..|.|   :|.||.:..:|.|.|||.|.|.||..:
 Worm   202 SGRY------ELLPSG---DLLIRKIQWSDMGSYFCIAHNKYGESR 238

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Dscam2NP_001261500.1 Ig 30..128 CDD:472250
Ig strand B 49..53 CDD:409353
Ig strand C 62..66 CDD:409353
Ig strand E 86..90 CDD:409353
Ig strand F 106..111 CDD:409353
Ig strand G 119..123 CDD:409353
V-set 138..229 CDD:462230
Ig 238..327 CDD:472250
Ig strand B 255..259 CDD:409353
Ig strand C 268..272 CDD:409353
Ig strand E 293..297 CDD:409353
Ig strand F 307..312 CDD:409353
Ig strand G 320..323 CDD:409353
Ig 330..418 CDD:472250
Ig strand B 348..352 CDD:409353
Ig strand C 365..369 CDD:409353
Ig strand E 383..387 CDD:409353
Ig strand F 397..402 CDD:409353
Ig strand G 411..414 CDD:409353
IgI_4_Dscam 422..517 CDD:409548
Ig strand A 422..425 CDD:409548
Ig strand A' 431..435 CDD:409548
Ig strand B 438..447 CDD:409548
Ig strand C 452..458 CDD:409548
Ig strand C' 460..463 CDD:409548
Ig strand D 468..476 CDD:409548
Ig strand E 480..489 CDD:409548
Ig strand F 496..504 CDD:409548
Ig strand G 507..517 CDD:409548
IgI_5_Dscam 521..608 CDD:409550
Ig strand A 521..523 CDD:409550
Ig strand A' 528..532 CDD:409550
Ig strand B 535..542 CDD:409550
Ig strand C 549..555 CDD:409550
Ig strand C' 556..558 CDD:409550
Ig strand D 565..569 CDD:409550
Ig strand E 572..578 CDD:409550
Ig strand F 586..594 CDD:409550
Ig strand G 598..608 CDD:409550
Ig 611..704 CDD:472250 4/21 (19%)
Ig strand B 630..634 CDD:409353
Ig strand C 644..648 CDD:409353
Ig strand E 670..674 CDD:409353
Ig strand F 684..689 CDD:409353 0/4 (0%)
Ig strand G 697..700 CDD:409353 0/2 (0%)
IgI_7_Dscam 707..802 CDD:409546 28/119 (24%)
Ig strand A 707..711 CDD:409546 1/3 (33%)
Ig strand A' 716..720 CDD:409546 1/4 (25%)
Ig strand B 723..732 CDD:409546 2/8 (25%)
Ig strand C 738..744 CDD:409546 2/5 (40%)
Ig strand C' 750..753 CDD:409546 1/2 (50%)
Ig strand D 761..764 CDD:409546 1/2 (50%)
Ig strand E 767..773 CDD:409546 2/14 (14%)
Ig strand F 780..788 CDD:409546 4/7 (57%)
Ig strand G 793..802 CDD:409546 1/8 (13%)
Ig 806..892 CDD:472250 25/85 (29%)
Ig strand B 823..827 CDD:409353 2/3 (67%)
Ig strand C 836..840 CDD:409353 1/3 (33%)
Ig strand E 868..872 CDD:409353 1/3 (33%)
Ig strand F 882..887 CDD:409353 3/4 (75%)
FN3 <904..1195 CDD:442628
FN3 906..1006 CDD:238020
fn3 1221..1306 CDD:394996
Ig 1336..1396 CDD:409353
Ig strand B 1336..1340 CDD:409353
Ig strand E 1371..1375 CDD:409353
Ig strand F 1385..1390 CDD:409353
FN3 <1407..>1606 CDD:442628
fn3 1408..1491 CDD:394996
zig-3NP_509336.1 Ig 45..145 CDD:472250 26/107 (24%)
Ig strand B 61..65 CDD:409548 1/3 (33%)
Ig strand C 74..78 CDD:409548 1/3 (33%)
Ig strand E 111..115 CDD:409548 0/3 (0%)
Ig strand F 125..130 CDD:409548 2/4 (50%)
Ig strand G 138..141 CDD:409548 0/2 (0%)
IG_like 177..244 CDD:214653 25/73 (34%)
Ig strand B 177..181 CDD:409353 2/3 (67%)
Ig strand C 188..192 CDD:409353 1/3 (33%)
Ig strand E 211..215 CDD:409353 2/6 (33%)
Ig strand F 225..230 CDD:409353 3/4 (75%)
Ig strand G 239..242 CDD:409353 62/241 (26%)
Blue background indicates that the domain is not in the aligned region.

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