DRSC/TRiP Functional Genomics Resources

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Protein Alignment Dscam2 and zig-8

DIOPT Version :9

Sequence 1:NP_001261500.1 Gene:Dscam2 / 38788 FlyBaseID:FBgn0265296 Length:2101 Species:Drosophila melanogaster
Sequence 2:NP_499714.1 Gene:zig-8 / 176732 WormBaseID:WBGene00006985 Length:268 Species:Caenorhabditis elegans


Alignment Length:259 Identity:71/259 - (27%)
Similarity:99/259 - (38%) Gaps:52/259 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   689 VRNSAAEVENSQALLVNVPPRWIVEPVDANVERNRHIMLHCQAQGVPTPSIVWKKATGSKSGEYE 753
            :|...:.|||....:|||            |..| ...|||.........|.|.:.:   .|...
 Worm    30 LRQERSRVENPSQTIVNV------------VAEN-PAYLHCSVPPDAEHEIAWTRVS---DGALL 78

  Fly   754 EVRERPFT---------KLLGNGSLLLQHVKEDREGFYLCQANNGIGTGIGKVIQLKVNSSPYFS 809
            ....|.||         |......|.|:..::...|.|||:.|:...|..  .:.|||...|..|
 Worm    79 TAGNRTFTRDPRWQVSKKSANIWVLNLRRAEQQDSGCYLCEINDKHNTVY--AVYLKVLEPPLPS 141

  Fly   810 STSRSVMVKK---------GDTALLQCAV-SGDKP---INIVWMRSGKNTL--NPSTNYKISVKQ 859
            .:|   :.||         ||..:|.|.| |.||.   :::||.|.| ||:  |.:..|.:.||:
 Worm   142 PSS---LQKKSTKLMANMSGDEVVLNCTVTSTDKDEEVLDVVWTRDG-NTINFNDTEKYILKVKR 202

  Fly   860 EATPDGVSAE-LQIRTVDATDSGPYFCRASNLYGNDQQLVQLQVQEPPLPPSVLEAAMISSRSV 922
            :|   ||..| ::||.....|.|.|.|..|....:  |:|.:...|.....|......|.|.|:
 Worm   203 DA---GVVIETMRIRKATMEDDGNYACEHSQQKAS--QIVHINKAEAQTSNSATFPCSIFSISI 261

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Dscam2NP_001261500.1 Ig 51..127 CDD:299845
Ig 138..>203 CDD:299845
I-set 238..327 CDD:254352
Ig 247..327 CDD:299845
I-set 332..418 CDD:254352
IGc2 344..407 CDD:197706
IG_like 432..517 CDD:214653
IGc2 436..507 CDD:197706
I-set 521..610 CDD:254352
IGc2 533..597 CDD:197706
Ig 630..699 CDD:143165 3/9 (33%)
IG_like 714..802 CDD:214653 21/96 (22%)
Ig 725..802 CDD:299845 19/85 (22%)
Ig 823..894 CDD:143165 27/77 (35%)
FN3 906..1006 CDD:238020 4/17 (24%)
FN3 1013..1111 CDD:238020
FN3 1119..1209 CDD:238020
FN3 1219..1313 CDD:238020
Ig 1336..1402 CDD:143165
FN3 1409..1498 CDD:238020
FN3 1515..1588 CDD:238020
zig-8NP_499714.1 IG_like 55..134 CDD:214653 19/83 (23%)
Ig 55..129 CDD:143165 18/78 (23%)
ig 158..229 CDD:278476 28/74 (38%)
IG_like 158..227 CDD:214653 27/72 (38%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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