DRSC/TRiP Functional Genomics Resources

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Protein Alignment Dscam2 and Il1r1

DIOPT Version :9

Sequence 1:NP_001261500.1 Gene:Dscam2 / 38788 FlyBaseID:FBgn0265296 Length:2101 Species:Drosophila melanogaster
Sequence 2:NP_032388.1 Gene:Il1r1 / 16177 MGIID:96545 Length:576 Species:Mus musculus


Alignment Length:333 Identity:75/333 - (22%)
Similarity:121/333 - (36%) Gaps:69/333 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   271 WFTHNGAGPLPVLSGPRVRLLGPILAIEAVTGEDSGVYKCTAGNVGGEASAELRLTVATPIQVEI 335
            |:.::...|:......|:......|.......||||.|.|...|     |.....|..|...:|.
Mouse    60 WYKNDSKTPISADRDSRIHQQNEHLWFVPAKVEDSGYYYCIVRN-----STYCLKTKVTVTV
LEN 119

  Fly   336 SPNVL---------SVHMGGTAEFRCLVTS------NGSPVGMQNILWYKDGRQL----PSSGRV 381
            .|.:.         .:|:.|.....|...|      |..|    .:.|||:.:.|    .|...|
Mouse   120 DPGLCYSTQATFPQRLHIAGDGSLVCPYVSYFKDENNELP----EVQWYKNCKPLLLDNVSFFGV 180

  Fly   382 EDTLVVPRVSRENRGMYQCVVRRP-EGDTFQATAELQL-------GDAPPVLLYSFIEQTLQ--P 436
            :|.|:|..|:.|:||.|.|.:... .|..:..|..:|.       .|.|.:|  |...:|::  |
Mouse   181 KDKLLVRNVAEEHRGDYICRMSYTFRGKQYPVTRVIQFITIDENKRDRPVIL--SPRNETIEADP 243

  Fly   437 GPAVSLKCSAAGNPTPQISWTLDGFPLPSNGRFMIGQYITVHG-------DVISHVNISHVMVE- 493
            |..:.|.|:..|..:..:.|..:|..:..|..|:...|..|..       .:|:.:|||.|..: 
Mouse   244 GSMIQLICNVTGQFSDLVYWKWNGSEIEWNDPFLAEDYQFVEHPSTKRKYTLITTLNISEVKSQF 308

  Fly   494 DGGEYACIAENRAGRVQHAARLNIYGLPYIRLIPKVT-----AVSG---ETLNLKCPVAGYPIEE 550
            ....:.|:.:|          .||:...:::||..|.     .:.|   .|..:.|.|..|.:.:
Mouse   309 YRYPFICVVKN----------TNIFESAHVQLIYPVPDFKNYLIGGFIILTATIVCCVCIYKVFK 363

  Fly   551 IH---WER 555
            :.   |.|
Mouse   364 VDIVLWYR 371

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Dscam2NP_001261500.1 Ig 51..127 CDD:299845
Ig 138..>203 CDD:299845
I-set 238..327 CDD:254352 12/55 (22%)
Ig 247..327 CDD:299845 12/55 (22%)
I-set 332..418 CDD:254352 25/105 (24%)
IGc2 344..407 CDD:197706 20/73 (27%)
IG_like 432..517 CDD:214653 19/94 (20%)
IGc2 436..507 CDD:197706 18/78 (23%)
I-set 521..610 CDD:254352 10/46 (22%)
IGc2 533..597 CDD:197706 7/29 (24%)
Ig 630..699 CDD:143165
IG_like 714..802 CDD:214653
Ig 725..802 CDD:299845
Ig 823..894 CDD:143165
FN3 906..1006 CDD:238020
FN3 1013..1111 CDD:238020
FN3 1119..1209 CDD:238020
FN3 1219..1313 CDD:238020
Ig 1336..1402 CDD:143165
FN3 1409..1498 CDD:238020
FN3 1515..1588 CDD:238020
Il1r1NP_032388.1 Ig 31..116 CDD:386229 14/60 (23%)
Ig2_IL1R_like 131..220 CDD:319309 24/92 (26%)
Ig_3 229..319 CDD:372822 21/91 (23%)
TIR 387..542 CDD:214587
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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