DRSC/TRiP Functional Genomics Resources

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Protein Alignment Dscam2 and Opcml

DIOPT Version :9

Sequence 1:NP_001261500.1 Gene:Dscam2 / 38788 FlyBaseID:FBgn0265296 Length:2101 Species:Drosophila melanogaster
Sequence 2:XP_017450901.1 Gene:Opcml / 116597 RGDID:620635 Length:354 Species:Rattus norvegicus


Alignment Length:351 Identity:84/351 - (23%)
Similarity:132/351 - (37%) Gaps:67/351 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly   602 RSGEVTVIVPPKLSPFQTNILQLNMGDRASLTCSVVKGDLPLTINW---------RKDGRPIDPT 657
            |||:.|.       |...:.:.:..|:.|:|.|::  .|....:.|         ..|...|||.
  Rat    32 RSGDATF-------PKAMDNVTVRQGESATLRCTI--DDRVTRVAWLNRSTILYAGNDKWSIDPR 87

  Fly   658 QHMSVKQVDQYNSILVIENLGSDHTGNYSCVVRNSAAEVENSQALLVNVPPRWIVEPVDANVERN 722
            ..:.|....||:  ::|:|:.....|.|:|.|:.......:...|:|.|||:.:....|..|...
  Rat    88 VIILVNTPTQYS--IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEG 150

  Fly   723 RHIMLHCQAQGVPTPSIVW-----KKATGSKS-GEYEEVRERPFTKLLGNGSLLLQHVKEDREGF 781
            ..:.|.|.|.|.|.|::.|     |:..|..| .||.|:.:                :|.|:.|.
  Rat   151 SSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISD----------------IKRDQSGE 199

  Fly   782 YLCQANNGIGTGIGKVIQLKVNSSPYFSSTSRSVMVKKGDTALLQCAVSGDKPINIVWMRSGKNT 846
            |.|.|.|.:.....:.:::.||..||.|. :::..|..|...:|.|..|........|       
  Rat   200 YECSALNDVAAPDVRKVKITVNYPPYISK-AKNTGVSVGQKGILSCEASAVPMAEFQW------- 256

  Fly   847 LNPSTNYKISVKQEATPDGVSAE-------LQIRTVDATDSGPYFCRASNLYGNDQQLVQLQVQE 904
                  :|...:.....|||..|       |....|...|.|.|.|.|:|..||....:.|....
  Rat   257 ------FKEDTRLATGLDGVRIENKGRISTLTFFNVSEKDYGNYTCVATNKLGNTNASITLYEIS 315

  Fly   905 PPL----PPSVLEAAMISSRSVNIKW 926
            |..    |.:|::....:||::...|
  Rat   316 PSSAVAGPGAVIDGVNSASRALACLW 341

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Dscam2NP_001261500.1 Ig 51..127 CDD:299845
Ig 138..>203 CDD:299845
I-set 238..327 CDD:254352
Ig 247..327 CDD:299845
I-set 332..418 CDD:254352
IGc2 344..407 CDD:197706
IG_like 432..517 CDD:214653
IGc2 436..507 CDD:197706
I-set 521..610 CDD:254352 4/7 (57%)
IGc2 533..597 CDD:197706
Ig 630..699 CDD:143165 18/77 (23%)
IG_like 714..802 CDD:214653 22/93 (24%)
Ig 725..802 CDD:299845 20/82 (24%)
Ig 823..894 CDD:143165 18/77 (23%)
FN3 906..1006 CDD:238020 5/25 (20%)
FN3 1013..1111 CDD:238020
FN3 1119..1209 CDD:238020
FN3 1219..1313 CDD:238020
Ig 1336..1402 CDD:143165
FN3 1409..1498 CDD:238020
FN3 1515..1588 CDD:238020
OpcmlXP_017450901.1 Ig 44..132 CDD:416386 20/91 (22%)
Ig strand A' 44..49 CDD:409353 0/4 (0%)
Ig strand B 51..59 CDD:409353 3/7 (43%)
CDR1 59..63 CDD:409353 1/5 (20%)
FR2 64..70 CDD:409353 1/5 (20%)
Ig strand C 64..70 CDD:409353 1/5 (20%)
CDR2 71..83 CDD:409353 1/11 (9%)
Ig strand C' 72..76 CDD:409353 0/3 (0%)
Ig strand C' 80..83 CDD:409353 1/2 (50%)
FR3 84..118 CDD:409353 11/35 (31%)
Ig strand D 87..94 CDD:409353 1/6 (17%)
Ig strand E 97..103 CDD:409353 2/7 (29%)
Ig strand F 110..118 CDD:409353 3/7 (43%)
CDR3 119..123 CDD:409353 0/3 (0%)
Ig strand G 123..132 CDD:409353 1/8 (13%)
FR4 125..132 CDD:409353 1/6 (17%)
Ig_3 135..206 CDD:404760 23/86 (27%)
Ig strand A 135..138 CDD:409353 2/2 (100%)
Ig strand A' 144..148 CDD:409353 1/3 (33%)
Ig strand B 151..160 CDD:409353 2/8 (25%)
Ig strand C 165..170 CDD:409353 1/4 (25%)
Ig strand C' 171..174 CDD:409353 0/2 (0%)
Ig strand F 198..206 CDD:409353 4/7 (57%)
Ig_3 223..300 CDD:404760 21/90 (23%)
putative Ig strand A 224..230 CDD:409353 3/6 (50%)
Ig strand B 240..244 CDD:409353 1/3 (33%)
Ig strand C 253..257 CDD:409353 1/16 (6%)
Ig strand E 279..283 CDD:409353 1/3 (33%)
Ig strand F 293..298 CDD:409353 2/4 (50%)
Ig strand G 306..309 CDD:409353 0/2 (0%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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