DRSC/TRiP Functional Genomics Resources

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Protein Alignment Dscam2 and lrit3b

DIOPT Version :9

Sequence 1:NP_001261500.1 Gene:Dscam2 / 38788 FlyBaseID:FBgn0265296 Length:2101 Species:Drosophila melanogaster
Sequence 2:XP_009305418.1 Gene:lrit3b / 100144406 ZFINID:ZDB-GENE-070424-130 Length:487 Species:Danio rerio


Alignment Length:334 Identity:76/334 - (22%)
Similarity:105/334 - (31%) Gaps:131/334 - (39%)


- Green bases have known domain annotations that are detailed below.


  Fly   267 PE--YSWFTHNGAGPLPV-------------LSG--------------PRVRLLG---------P 293
            ||  |.|.|:|....|..             |.|              ||:|.||         |
Zfish   112 PELLYLWLTYNSISVLHPRSFTNLSSLHELRLDGNLLSTFPWEGLRDMPRLRTLGLHNNRLARIP 176

  Fly   294 ILAIEAVTGEDSGVYKCTAGNVGGEASAELRLTVATPIQVEISPNVLSVHMGGTAEFRCLVTSNG 358
            :||:..:.            ||               ..:::|.|.||..............||.
Zfish   177 LLAVRYLR------------NV---------------TYLDLSSNRLSTLANDLTALWLFSDSNQ 214

  Fly   359 SP----VGMQNILWYKDGRQLPSSGRVEDTLVVPRVSRENRGMYQCVVRRPEG-----DTFQATA 414
            :.    :|:|:..|..|.|.        .||:             .:.|.||.     |.|...:
Zfish   215 TQRSFVLGLQDNPWVCDCRL--------STLL-------------DISRGPESSLVLLDRFLTCS 258

  Fly   415 E-LQLGDAP-----------PVLLYSFIEQTLQPGPAVSLKCSAAGNPTPQISW----------- 456
            | |.|...|           |.::.|..:.|...|..|.|:|.|.|:|||.:.|           
Zfish   259 EPLDLAGVPFQSVELSRCRRPYVVTSATKITALLGSTVLLRCEATGHPTPALMWIKSAKRNLYNQ 323

  Fly   457 --------TLD--GFPLPSNGRFMIGQYITVHGDVISHVNISHVMVEDGGEYACIAENRAGRVQH 511
                    :||  .||....|.......:.|...|:|...||:   .|.|||.|.|:|.||..:.
Zfish   324 GCCKQTQSSLDTERFPKKLFGYVQESPRVGVRWSVVSLNGISY---SDAGEYRCRAQNMAGISEA 385

  Fly   512 AARLNIYGL 520
            ...||:.|:
Zfish   386 VVSLNVVGV 394

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Dscam2NP_001261500.1 Ig 51..127 CDD:299845
Ig 138..>203 CDD:299845
I-set 238..327 CDD:254352 19/97 (20%)
Ig 247..327 CDD:299845 19/97 (20%)
I-set 332..418 CDD:254352 20/95 (21%)
IGc2 344..407 CDD:197706 11/66 (17%)
IG_like 432..517 CDD:214653 31/105 (30%)
IGc2 436..507 CDD:197706 27/91 (30%)
I-set 521..610 CDD:254352 76/334 (23%)
IGc2 533..597 CDD:197706
Ig 630..699 CDD:143165
IG_like 714..802 CDD:214653
Ig 725..802 CDD:299845
Ig 823..894 CDD:143165
FN3 906..1006 CDD:238020
FN3 1013..1111 CDD:238020
FN3 1119..1209 CDD:238020
FN3 1219..1313 CDD:238020
Ig 1336..1402 CDD:143165
FN3 1409..1498 CDD:238020
FN3 1515..1588 CDD:238020
lrit3bXP_009305418.1 LRRNT 51..92 CDD:214470
leucine-rich repeat 69..89 CDD:275380
LRR_8 112..172 CDD:290566 14/59 (24%)
leucine-rich repeat 114..137 CDD:275378 5/22 (23%)
leucine-rich repeat 138..161 CDD:275378 2/22 (9%)
LRR_8 160..214 CDD:290566 15/80 (19%)
LRR_4 160..201 CDD:289563 14/67 (21%)
leucine-rich repeat 162..185 CDD:275378 6/34 (18%)
leucine-rich repeat 186..199 CDD:275378 5/27 (19%)
leucine-rich repeat 215..230 CDD:275378 3/14 (21%)
Ig 278..391 CDD:299845 33/115 (29%)
I-set 279..391 CDD:254352 33/114 (29%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

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