DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment msl-3 and Arid4b

DIOPT Version :9

Sequence 1:	NP_523951.1	Gene:	msl-3 / 38779	FlyBaseID:	FBgn0002775	Length:	512	Species:	Drosophila melanogaster
Sequence 2:	XP_008769986.1	Gene:	Arid4b / 84481	RGDID:	619919	Length:	1319	Species:	Rattus norvegicus

Alignment Length:	233	Identity:	46/233 - (19%)
Similarity:	87/233 - (37%)	Gaps:	51/233 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 CYEPDKSKARVLYTSKVLNVFERRNEHGLRFYE--------------YKIHFQGWRPSYDRCVRA 69
            ||.|. .|.:|.|.       ..:|:   :.||              |.:|:.||...||..::|
  Rat   568 CYPPG-MKVQVRYG-------RGKNQ---KMYEASIKDSDVEGGEVLYLVHYCGWNVRYDEWIKA 621

  Fly    70 TVLLKDTEEN-RQLQRELAEAAKLQIRGDYSYKGTPDKPSAKKKRGGKAAHVEEP---IVVPM-- 128
            ..:::..::| .:::.......||....|...|.:|  .:.|.:|..|:.....|   :|..:
  Rat   622 DKIVRPADKNVPKIKHRKKIKNKLDKEKDRDEKYSP--KNCKLRRLSKSPFQSNPSPEMVSKLDL 684

  Fly   129 ------DTGHLEA-------EHEMAPTPRAAGNRTRDNSGGKRKEKPPSGDGRLKGNRGRQTETF 180
                  ||||:::       ....|....|..:...:....:..|.....:.:::.:...::|..
  Rat   685 ADAKNSDTGHIKSIEITSILNGLQASESSAEDSEQEEERCAQDPESSSKDESKVEHSAHSRSELI 749

  Fly   181 YNNAINDVSVY--NHVPQEDRIMMRVS---ERLRELIE 213
            ....::..|:.  |.|..:..|...||   ||||:.:|
  Rat   750 SKEELSSPSLLEENKVHPDLVIAKTVSKSPERLRKDVE 787

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
msl-3	NP_523951.1	MRG	196..486	CDD:283390	8/21 (38%)
Arid4b	XP_008769986.1	TUDOR	58..113	CDD:197660
		RBB1NT	169..262	CDD:285392
		ARID	311..394	CDD:198082
		Tudor-knot	571..624	CDD:288553	14/63 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3001
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900