DRSC/TRiP Functional Genomics Resources

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Protein Alignment msl-3 and ARID4B

DIOPT Version :9

Sequence 1:NP_523951.1 Gene:msl-3 / 38779 FlyBaseID:FBgn0002775 Length:512 Species:Drosophila melanogaster
Sequence 2:NP_001193723.1 Gene:ARID4B / 51742 HGNCID:15550 Length:1312 Species:Homo sapiens


Alignment Length:351 Identity:71/351 - (20%)
Similarity:119/351 - (33%) Gaps:101/351 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    19 CYEPDKSKARVLYTSKVLNVFERRNEHGLRFYE--------------YKIHFQGWRPSYDRCVRA 69
            ||.|. .|.:|.|.       ..:|:   :.||              |.:|:.||...||..::|
Human   568 CYPPG-MKVQVRYG-------RGKNQ---KMYEASIKDSDVEGGEVLYLVHYCGWNVRYDEWIKA 621

  Fly    70 TVLLKDTEEN-RQLQRELAEAAKLQIRGDYSYKGTPDKPSAKKKRGGKAAHVEEP---IVVPM-- 128
            ..:::..::| .:::.......||....|...|.:|  .:.|.:|..|......|   :|..:  
Human   622 DKIVRPADKNVPKIKHRKKIKNKLDKEKDKDEKYSP--KNCKLRRLSKPPFQTNPSPEMVSKLDL 684

  Fly   129 ------DTGHL---------------EAEHEMAPTPRAAGNRTRDNSGGKRKEKPPSGDGRLKGN 172
                  ||.|:               |:..|.:......|.:..||:|     |..|....|..|
Human   685 TDAKNSDTAHIKSIEITSILNGLQASESSAEDSEQEDERGAQDMDNNG-----KEESKIDHLTNN 744

  Fly   173 RGRQTETFYNNAINDVSVYNHVPQEDRIMMRVS---ERLRELIEYDRNMIKVLGKQHALPARVPI 234
            |.........|: :.:...|.|..:..|...||   ||||:.||       ||.:.         
Human   745 RNDLISKEEQNS-SSLLEENKVHADLVISKPVSKSPERLRKDIE-------VLSED--------- 792

  Fly   235 VTIMENFVKQQAVELAISIKQDSSRARNTQSRNARMEREYDRVMSTVCMLKEVVDGLRIYFEFHV 299
                .::.:.:..:....:|:|::    .:|...:::|...|..:|...||....|.:       
Human   793 ----TDYEEDEVTKKRKDVKKDTT----DKSSKPQIKRGKRRYCNTEECLKTGSPGKK------- 842

  Fly   300 DDHLLYTEEKEYVHNYLTDDNMRNCS 325
                   |||......|..:|..|.|
Human   843 -------EEKAKNKESLCMENSSNSS 861

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
msl-3NP_523951.1 MRG 196..486 CDD:283390 27/133 (20%)
ARID4BNP_001193723.1 TUDOR 58..113 CDD:197660
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 124..166
RBB1NT 170..262 CDD:285392
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 266..306
ARID 311..394 CDD:198082
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 458..577 4/9 (44%)
Antigenic epitope 465..473
Tudor-knot 571..624 CDD:288553 14/63 (22%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 635..680 9/46 (20%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 708..894 41/198 (21%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 909..1212
Antigenic epitope 1130..1137
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1252..1288
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3001
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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