DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8641 and rasd1

DIOPT Version :9

Sequence 1:	NP_001261494.1	Gene:	CG8641 / 38771	FlyBaseID:	FBgn0035733	Length:	434	Species:	Drosophila melanogaster
Sequence 2:	NP_001072408.1	Gene:	rasd1 / 779862	XenbaseID:	XB-GENE-483475	Length:	266	Species:	Xenopus tropicalis

Alignment Length:	271	Identity:	137/271 - (50%)
Similarity:	184/271 - (67%)	Gaps:	23/271 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   164 KNCYRLVMLGSSRAGKSSIVARFLGNRFEEAYTPTIEEFHRKLYRIRNEVFQLDILDTSGYHPFP 228
            |||||:|:||||:.||:|||:|||..||||.||||||:||||.|.||.||:|||||||||.||||
Frog    17 KNCYRMVILGSSKVGKTSIVSRFLSGRFEEQYTPTIEDFHRKFYSIRGEVYQLDILDTSGNHPFP 81

  Fly   229 AMRRLSFLTGDLFILVFSMDSRESFEEVVRLRENILETKWAALNPGSGFKKKSLPKIPMILAGNK 293
            ||||||.||||:||||||:|:|:|||||.||::.|:|||....|     |.|....:|:::.|||
Frog    82 AMRRLSILTGDVFILVFSLDNRDSFEEVQRLKQQIIETKSCLKN-----KTKENVDVPIVICGNK 141

  Fly   294 CDRDF-KTVQVDEVMGYIAGQDNCCTFVECSARQNYRIDDLFHSLFTVSNLPLEMTPNHHRRLVS 357
            .|||| :.||..|: ..:.|:|:.|::.|.||::|..:|::|.:|||::.||.||:|:.||: ||
Frog   142 VDRDFYREVQPHEI-EQLVGEDSKCSYFEVSAKKNSSLDEMFKALFTMAKLPSEMSPDLHRK-VS 204

  Fly   358 VFGAPSPLPPHGSAVGGTKKNALSIKRRFSDACGVVTPNARRPSIRTDLNLMRSKTMALNEGEGV 422
            |.....   .|..::.|.|      .:...||.|:|.|.||||||.:||..:|:|.:.     |.
Frog   205 VQYCEI---LHKKSLKGKK------VKEDGDAYGIVAPFARRPSIHSDLMYIRAKAVG-----GG 255

  Fly   423 RSPSRWNRCAL 433
            :|..: .||.:
Frog   256 QSKDK-ERCVI 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8641	NP_001261494.1	Rhes_like	167..434	CDD:133343	134/268 (50%)
CG8641	NP_001261494.1	RAS	167..338	CDD:214541	99/171 (58%)
rasd1	NP_001072408.1	Rhes_like	20..266	CDD:133343	134/268 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	197	1.000	Domainoid score	I3050
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H7509
Inparanoid	1	1.050	243	1.000	Inparanoid score	I3229
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1398885at2759
OrthoFinder	1	1.000	-	-		FOG0005519
OrthoInspector	1	1.000	-	-		otm47504
Panther	1	1.100	-	-	LDO	PTHR46149
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5615
SonicParanoid	1	1.000	-	-		X3937
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	12.100