Protein Alignment CG8641 and RASL11A

DIOPT Version :10

• Sequence 1: NP_648073.1
• Gene: CG8641 / 38771
• FlyBaseID: FBgn0035733
• Length: 434
• Species: Drosophila melanogaster
• Sequence 2: NP_996563.1
• Gene: RASL11A / 387496
• HGNCID: 23802
• Length: 242
• Species: Homo sapiens
• Alignment Length: 290
• Identity: 71/290 - (24%)
• Similarity: 122/290 - (42%)
• Gaps: 81/290 - (27%)

  Fly   139 IEQADDFIYGPGAGLSLCDDSLPSAKNCY------RLVMLGSSRAGKSSIVARFLGNRFEEAYTP 197
            :..:..|:..|          :|.:.:.|      :|.:||:.|.|||:::.|||..||...|.|
Human     4 LSMSGHFLLAP----------IPESSSDYLLPKDIKLAVLGAGRVGKSAMIVRFLTKRFIGDYEP 58

  Fly   198 TIEEFHRKLYRIRNEVFQLDILDTSG----YHPFPAM-----RRLSFLTGDLFILVFSMDSRESF 253
            ...:.:.:|..:..:...|.|.||.|    ....|.:     :.:.:..|  |:||:|:...:|:
Human    59 NTGKLYSRLVYVEGDQLSLQIQDTPGGVQIQDSLPQVVDSLSKCVQWAEG--FLLVYSITDYDSY 121

  Fly   254 EEVVRLRENILETKWAALNPGSGFKKKSLPKIPMILAGNKCD----RDFKT---VQVDEVMGYIA 311
            ..:..|.::|.:     ::|.|        |.|:|:.|||.|    |..:|   :|:...:|.:
Human   122 LSIRPLYQHIRK-----VHPDS--------KAPVIIVGNKGDLLHARQVQTQDGIQLANELGSL- 172

  Fly   312 GQDNCCTFVECSARQNYR-IDDLFHSLFTVSNLPLEMTPNH----HRRLVSVFGAPSPLPPHGSA 371
                   |:|.|..:||. :.|:|      .:|..|::..|    .||..|:.  |.|..|
Human   173 -------FLEISTSENYEDVCDVF------QHLCKEVSKMHGLSGERRRASII--PRPRSP---- 218

  Fly   372 VGGTKKNALSIKRRFSDACGVVTPNARRPS 401
                  |...:||||..|   ::|..:.||
Human   219 ------NMQDLKRRFKQA---LSPKVKAPS 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8641	NP_648073.1	Rhes_like	167..434	CDD:133343	68/262 (26%)
RASL11A	NP_996563.1	Small GTPase-like	17..241		68/267 (25%)
		RERG_RasL11_like	29..198	CDD:206713	51/197 (26%)