Protein Alignment CG8641 and ERAS

DIOPT Version :10

• Sequence 1: NP_648073.1
• Gene: CG8641 / 38771
• FlyBaseID: FBgn0035733
• Length: 434
• Species: Drosophila melanogaster
• Sequence 2: NP_853510.1
• Gene: ERAS / 3266
• HGNCID: 5174
• Length: 233
• Species: Homo sapiens
• Alignment Length: 181
• Identity: 46/181 - (25%)
• Similarity: 76/181 - (41%)
• Gaps: 37/181 - (20%)

  Fly   167 YRLVMLGSSRAGKSSIVARFLGNRFEEAYTPTIEEFHRKLYRIRNEVFQLDILDTSGYHPFPAMR 231
            |:.|::|:|..|||::..:.....|.|.:.|||::.:.|...:.:....|::|||:|.....|:|
Human    42 YKAVVVGASGVGKSALTIQLNHQCFVEDHDPTIQDSYWKELTLDSGDCILNVLDTAGQAIHRALR 106

  Fly   232 RLSFLTGDLFILVFSMDSRESFEEVVRLRENILETKWAALNPGSGFKKKSLPKIPMILAGNKCDR 296
            .......|..:.||::|...|..:        |:..||...|.        |..|::|.|||||
Human   107 DQCLAVCDGVLGVFALDDPSSLIQ--------LQQIWATWGPH--------PAQPLVLVGNKCD- 154

  Fly   297 DFKTVQVDEVMGYIAGQDNCCT----------FVECSARQNYRIDDLFHSL 337
                      :...||..:...          |||.||:....:::.|..|
Human   155 ----------LVTTAGDAHAAAAALAHSWGAHFVETSAKTRQGVEEAFSLL 195

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8641	NP_648073.1	Rhes_like	167..434	CDD:133343	46/181 (25%)
ERAS	NP_853510.1	RalA_RalB	42..201	CDD:206710	46/181 (25%)
		Effector region	70..78		3/7 (43%)