Protein Alignment CG8641 and RASD2

DIOPT Version :9

• Sequence 1: NP_001261494.1
• Gene: CG8641 / 38771
• FlyBaseID: FBgn0035733
• Length: 434
• Species: Drosophila melanogaster
• Sequence 2: XP_016884190.1
• Gene: RASD2 / 23551
• HGNCID: 18229
• Length: 278
• Species: Homo sapiens
• Alignment Length: 269
• Identity: 131/269 - (48%)
• Similarity: 180/269 - (66%)
• Gaps: 26/269 - (9%)

  Fly   156 CDDSLPSAKNCYRLVMLGSSRAGKSSIVARFLGNRFEEAYTPTIEEFHRKLYRIRNEVFQLDILD 220
            |..|:| |||.||:|:||:||.||||||:|||..|||:.||||||:||||:|.||.:::||||||
Human    22 CTLSVP-AKNSYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILD 85

  Fly   221 TSGYHPFPAMRRLSFLTGDLFILVFSMDSRESFEEVVRLRENILETKWAALNPGSGFKKKSLPKI 285
            |||.||||||||||.||||:||||||:|:||||:||.||::.|||.|....|     |.|...::
Human    86 TSGNHPFPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKN-----KTKEAAEL 145

  Fly   286 PMILAGNKCDRD--FKTVQVDEVMGYIAGQDNCCTFVECSARQNYRIDDLFHSLFTVSNLPLEMT 348
            ||::.|||.|..  .:.|...|....::|.:||..| |.||::|..:|::|:.||:::.||.||:
Human   146 PMVICGNKNDHGELCRQVPTTEAELLVSGDENCAYF-EVSAKKNTNVDEMFYVLFSMAKLPHEMS 209

  Fly   349 PNHHRRLVSVFG-APSPLPPHGSAVGGTKKNALSIKR-RFSDACGVVTPNARRPSIRTDLNLMRS 411
            |..||::...:| |..|.|             ..::| :..||.|:|:|.|||||:.:||..:::
Human   210 PALHRKISVQYGDAFHPRP-------------FCMRRVKEMDAYGMVSPFARRPSVNSDLKYIKA 261

  Fly   412 KTMALNEGE 420
            |  .|.||:
Human   262 K--VLREGQ 268

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8641	NP_001261494.1	Rhes_like	167..434	CDD:133343	125/258 (48%)
		RAS	167..338	CDD:214541	95/172 (55%)
RASD2	XP_016884190.1	Rhes_like	32..278	CDD:133343	125/258 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	191	1.000	Domainoid score	I3248
eggNOG	1	0.900	-	-		E2759_KOG0395
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	234	1.000	Inparanoid score	I3413
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1398885at2759
OrthoFinder	1	1.000	-	-		FOG0005519
OrthoInspector	1	1.000	-	-		otm40330
orthoMCL	1	0.900	-	-		OOG6_107719
Panther	1	1.100	-	-	O	PTHR46149
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5615
SonicParanoid	1	1.000	-	-		X3937
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.860